A Explorative Pilot Study to Gain Insights for a New Senior Milk Powder

Inclusion criteria

• • Age 50-70 years (bounds included)

• Body Mass Index (BMI) between 18.5 (bound included) and 30 (bound excluded) kg/m2.
• Ability to comply with the protocol and assessment window:
• Product intake according to instructions.
• Willing to collect, store, deliver stool sample according to instructions.

• Willing to adhere to instructions and restrictions during entire study period*:
• No probiotic supplementations or products supplemented with probiotics.
• No dietary fiber supplements.
• No medications may modify gastrointestinal function.

• Fluency in speaking, reading and writing in mandarin.
• Capability of the subject to install and use the secure study platform on the smartphone during entire study period.
• Written informed consent. *Overruled in case of medical needs.

Exclusion criteria

• • Known / Existing gastrointestinal diseases or disorders diagnosed by a physician that may interfere with study.

• Known / Existing milk protein allergies, lactose intolerance or other allergies to product ingredients.
• Known / Existing immune diseases or disorders diagnosed by a physician that may interfere with study.
• Use of any medication may modify gastrointestinal function: tricyclic antidepressants, SSRIs/antidepressants, opioids, ACE inhibitor, bate sympathomimetics, systemic antibiotics, intestinal antiseptics, anti-inflammatory medicines (including nonsteroidal anti-inflammatory drugs [NSAIDs] and aspirin), anti-histamines, steroids, corticosteroids, laxatives, anti-diarrhoea medication, prokinetics/dopamine-antagonists, metformin, statins, or any other stomach medication (including proton pump inhibitor [PPIs], antiacids, and antihistamine2 blockers) within 8 weeks prior to enrolment.
• Consumption of probiotic supplementations or products supplemented with probiotics within 4 weeks prior to enrolment.
• Subject following a special diet, including but not limited to vegan diet, ketogenic diet, low fiber diet, thickening diet etc.
• Incapability to comply with protocol as per the judgement of the investigator.
• Participation in any other studies involving investigational or marketed products concomitantly or 2 weeks prior to enrolment.
• Employees and/or children/family member or relatives of employees of Danone or the participating site.