A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different Products

Sutures are an integral part of surgery and available materials are diverse, as are the options for post-procedure care. Both saline and hydrogen peroxide are commonly used cleansing agents. This study aims to compare the effect of saline and hydrogen peroxide on the tensile strength of 4-0 nylon sutures following removal from a cutaneous surgical wound.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Sutured Wounds Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Miami Hospital and Clinics/Sylvester Comprehensive Cancer Center

Miami, Florida, 33136, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Subject is willing to comply with the informed consent procedures
Subject's wound is on the body or scalp
Subject will be able to come to the clinic for suture removal on day 14

Exclusion criteria

Subject is less than 18 years of age
Subject's wound was not closed with 4-0 nylon sutures
Subject's wound is on the face
Subject plans to apply other topicals to the area under study
Subject's suture is removed before or after day 14

Treatment and study plan

Hydrogen peroxide

Other

Once daily topical application of 3% hydrogen peroxide using a cotton-tipped applicator

Saline

Other

Once daily topical application of normal saline, using a cotton-tipped applicator

Primary outcomes

Tensile strength of 4-0 nylon sutures

Time frame: 14 days

The tensile strength was defined as the force required to break the suture, with breaking strength as the maximum strength that a material can withstand when subjected to an applied load, without taking into consideration the cross sectional area. The strength of the sutures was measured using a tensometer.

Sponsors and collaborators

Lead sponsor

University of Miami

Other

Registry information

Official study title

A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different

Important dates

Study start: 2010
Primary completion: 2011
Study completion: 2011
First posted: Feb 15, 2012
Registry last updated: May 10, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed