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OpenTrials
Completed

NCT Number: NCT00655109

A Comparison of Olopatadine and Fluticasone in Patients With Allergic Conjunctivitis

To compare the clinical efficacy of olopatadine and fluticasone in a 3-week single center, double-masked, randomized, placebo controlled parallel treatment conjunctival allergen challenge (CAC) study in patients with allergic conjunctivitis

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Key information

Conditions

Conjunctivitis, Allergic Conjunctival Diseases Conjunctivitis Eye Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Ophthalmic Research Associates, Inc

North Andover, Massachusetts, 01845, United States

About this study

Study will evaluate the efficacy of nasal anti-allergic therapy compared to ocular anti-allergic therapy in the prevention of ocular allergic symptoms.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • At least 18 years of age & either sex, any race
  • Willing and able to follow all instructions and attend all study visits
  • Positive history of ocular allergies
  • Reproducible positive ocular allergic reaction induced by conjunctival allergen challenge

Exclusion criteria

  • Have planned surgery during trial period
  • Female currently pregnant, planning a pregnancy, or lactating
  • Use of disallowed medications

Treatment and study plan

Olopatadine

Drug

Ophthalmic solution

Fluticasone

Drug

Nasal spray

Saline

Drug

Nasal spray

Artificial Tears

Drug

Ophthalmic Solution

Primary outcomes

  1. Ocular itching

    Time frame: Minutes following CAC

Secondary outcomes

  1. Ocular redness

    Time frame: Minutes following CAC

Sponsors and collaborators

Lead sponsor

Greiner, Jack V., OD DO PhD

Indiv

Registry information

Official study title

A Comparison of Olopatadine Versus Fluticasone Nasal Spray in the Prevention of the Signs and Symptoms of Allergic Conjunctivitis

Important dates

Study start
2008
Primary completion
2008
Study completion
2008
First posted
Apr 9, 2008
Registry last updated
Apr 9, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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