A Comparison of LY2963016 to a Basal Insulin After a Single Dose in Healthy Subjects

Inclusion criteria

• Are overtly healthy males or females
• Have a body mass index (BMI) between 18.5 and 29.9 kilogram per square meter (kg/m^2)
• Are nonsmokers
• Have normal blood pressure and pulse rate
• Have an electrocardiogram (ECG) considered as within normal limits
• Have clinical laboratory test results within normal reference range

Exclusion criteria

• Are currently enrolled in, or discontinued within the last 30 days from, a clinical trial involving an investigational drug or device
• Have known allergies to insulin or its excipients
• Have significant history of or current cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrine, hematological, or neurological disorders
• Show evidence of significant active neuropsychiatric disease
• Have a history of first-degree relatives known to have diabetes mellitus
• Have a fasting venous blood glucose >6.0 millimoles per liter (mmol/L)
• Intend to use over-the-counter or prescription medication
• Have donated or had a blood loss of 450 milliliters (mL) or more in the past 3 months
• Have an average weekly alcohol intake that exceeds 21 units per week (males) and 14 units per week (females)