Department of TMD and Orthodontics Silesian Medical University
Zabrze, 41-800, Poland
NCT Number: NCT03323567
An intramusclular injection of three solutions were performed( collagen, lidocaine, saline) in musculoskeletal trigger points, in patients suffering from temporomandibular disorders(TMD). Best results were observed in collagen group: reduction of 59,2% sEMG activity of masseter muscles and 53,75% reduction of pain intensity in VAS scale.
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Notify Me18 year–70 year
All sexes
Interventional
Early Phase 1
Zabrze, 41-800, Poland
Collagen is an important component, building myocytes and extracellular matrix of skeletal muscles. The novel treatment option for trigger point therapy and muscle regeneration in TMD patients are intramuscular collagen injections. The aim of the study was to evaluate the efficacy of intramuscular injections of Collagen MD Muscle(Guna) 2 ml, 2 ml of Lidocainum 2% without vasoconstrictor and 2 ml of Saline (0,9 % NaCl). 43 patients were enrolled to the study (17 male and 26 female, 40 +/- 3,8 years old). The masseter muscle activity was measured with sEMG Neurobit Optima 4 (Neurobit System). Visual Analogue Scale was used to determine pain intensity changes between follow-up visits in each group. Trigger points were localized with palpation of masseter muscle. Electromyographic activity of masseter muscle was measured before injections on each visit: 0, 7,14 days. In our analysis sEMG masseter muscle activity was significantly decreased: in collagen group 59,2%, in lidocainum group 39,3% and in saline group14%. Pain intensity reduction in VAS scale was 53,75% in collagen group, in lidocainum group 25% and in saline group 20,1%.
Healthy volunteers accepted: No
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Inclusion criteria
Exclusion criteria
intramusclular injections of MD Muscle collagen
Other names: intramuscular MD Muscle collagen injection
intramuscular Lidocaine 2% injection
Other names: intramuscular Lidocaine 2% injection
intramuscular Saline injection
Other names: intramuscular Saline injection
Time frame: 14 days
reduction of electromyograpic activity of masseter muscle
Medical University of Silesia
Other
A Comparison of Collagen, Lidocaine and Saline Intramuscular Injections, in Myofascial Pain Patients With Trigger Points in Masseter Muscle.
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