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OpenTrials
Completed

NCT Number: NCT02220595

A Comparison of Cognitive Function After Carotid Endarterectomy and Stenting

This study compares cognitive function after carotid endarterectomy and stenting.

Completed

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Key information

Conditions

Carotid Artery Occlusive Disease

Age range

30 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Michael E. Debakey VAMC

Houston, Texas, 77030, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Carotid artery occlusive disease, asymptomatic greater than 80% with CTA or carotid duplex

Exclusion criteria

  • Contraindication for carotid endarterectomy or stenting

Treatment and study plan

Carotid endarterectomy vs. carotid stenting

Procedure

Primary outcomes

  1. Difference in RAVLT score

    Time frame: Six weeks

Secondary outcomes

  1. Cognitive tests for attention, memory, processing speed, mood, motor function, visual-spatial skills, executive functioning

    Time frame: Six weeks and six months

  2. Cognitive tests of attention

    Time frame: Six weeks

    Comparison in cognitive tests for attention between carotid endarterectomy and stenting

  3. Cognitive tests for memory

    Time frame: Six weeks

    Comparison in cognitive tests for memory between carotid endarterectomy and stenting

  4. Cognitive tests for processing speed

    Time frame: Six weeks

    Comparison in cognitive tests for processing speed between carotid endarterectomy and stenting

  5. Cognitive tests of mood

    Time frame: Six weeks

    Comparison in cognitive tests for mood between carotid endarterectomy and stenting

  6. Tests of motor function

    Time frame: Six weeks

    Comparison in cognitive tests for motor function between carotid endarterectomy and stenting

  7. Cognitive tests of visual-spatial skills

    Time frame: Six weeks

    Comparison in cognitive tests of visual-spatial skills between carotid endarterectomy and stenting

  8. Cognitive tests of executive functioning

    Time frame: Six weeks

    Comparison in cognitive tests for executive functioning between carotid endarterectomy and stenting

  9. Cognitive tests of attention

    Time frame: Six months

    Comparison in cognitive tests for attention between carotid endarterectomy and stenting

  10. Cognitive tests of memory

    Time frame: Six weeks

    Comparison in cognitive tests for memory between carotid endarterectomy and stenting

  11. Cognitive tests of processing speed

    Time frame: Six months

    Comparison in cognitive tests for processing speed between carotid endarterectomy and stenting

  12. Cognitive tests of mood

    Time frame: Six months

    Comparison in cognitive tests for mood between carotid endarterectomy and stenting

  13. Tests of motor function

    Time frame: Six months

    Comparison in cognitive tests for motor function between carotid endarterectomy and stenting

  14. Cognitive tests of visual-spatial skills

    Time frame: Six months

    Comparison in cognitive tests for visual-spatial skills between carotid endarterectomy and stenting

  15. Cognitive tests of executive functioning

    Time frame: Six months

    Comparison in cognitive tests for executive functioning between carotid endarterectomy and stenting

  16. Difference in new ischemic infarcts in Diffusion - weighted MRI

    Time frame: Six weeks

    Difference in new ischemic infarcts in Diffusion - weighted MRI

  17. Difference in new ischemic infarcts in Diffusion - weighted MRI

    Time frame: Six months

    Difference in new ischemic infarcts in Diffusion - weighted MRI

Sponsors and collaborators

Lead sponsor

Baylor College of Medicine

Other

Registry information

Important dates

Study start
2011
Primary completion
2013
Study completion
2014
First posted
Aug 20, 2014
Registry last updated
Aug 20, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.