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Completed

NCT Number: NCT07174024

A Comparative Study on the Efficacy of Blue Light Emitting Diodes Therapy Versus Targeted Narrow Band UVB in Stable Non-segmental Vitiligo Patients.

A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.

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Key information

Conditions

Vitiligo Hypopigmentation Pigmentation Disorders Skin Diseases Skin and Connective Tissue Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Cairo University

Giza, Cairo Governorate, 13114, Egypt

About this study

A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All age group.
  • Both genders.
  • Subjects with stable non-segmental vitiligo (≥2 patches) acral or non-acral patches of diameter ≤ 2cm.

Exclusion criteria

  • Prior treatment with laser therapies for at least 3 months
  • Recent exfoliation procedures.
  • Recent surgical procedures.
  • Poor skin conditions including keloids.
  • Hypersensitivity to light ( visible and near-infrared).
  • Medications that make users more sensitive to light.
  • Anticoagulant and immunosuppressive treatments.
  • Gestations or breastfeeding.
  • A personal or family history of skin cancer.
  • Unstable vitiligo (older lesions have not progressed for the last 1 years and lack of Koebner phenomena ).

Treatment and study plan

Narrow Band UVB Treatment

Device

type of phototherapy

blue light emitting diode

Device

type of diode

Primary outcomes

  1. Assess the degree of improvement in vitiligo pigmentation using VASI scores before and after treatment.

    Time frame: 48 weeks

    Assess the degree of improvement in vitiligo pigmentation using VASI scores before and after treatment.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Acronym: Nb-UVB

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 15, 2025
Registry last updated
Sep 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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