A Comparative Study Between Three Surgical Techniques in Large Angle Exotropia

This is a randomized comparative interventional study that aims to compare the surgical outcomes of correcting large angle exotropia (≥50 prism diopter) by three different surgical techniques including: 1/ bilateral lateral rectus muscle recession with unilateral medial rectus muscle resection 2/bilateral medial rectus muscle resection, 3/unilateral medial rectus muscle resection with lateral rectus muscle transplantation,

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Key information

Conditions

Exotropia Equal or More Than 50 Prism Diopter Cranial Nerve Diseases Exotropia Eye Diseases Nervous System Diseases Ocular Motility Disorders Strabismus

Age range

3 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This is a randomized comparative interventional study that will be conducted on patients with large angle exotropia before and after doing surgical correction using three different surgical techniques including : 1/ bilateral lateral rectus muscle recession with unilateral medial rectus muscle resection 2/bilateral medial rectus muscle resection, 3/unilateral medial rectus muscle resection with lateral rectus muscle transplantation ,to compare the surgical outcomes between them.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with large-angle exotropia (≥50 prism diopter).

Exclusion criteria

Patients with an exodeviation angle of less than 50 prism diopter.
History of previous strabismus surgery.
Restrictive or paretic strabismus or history of botulinum toxin injections for strabismus.

Treatment and study plan

Extropia squint surgery

Procedure

patients with large angle exotropia will be treated by three different surgical techniques including: 1/ bilateral lateral rectus muscle recession with unilateral medial rectus muscle resection 2/bilateral medial rectus muscle resection, 3/unilateral medial rectus muscle resection with lateral rectus muscle transplantation ,to compare the surgical outcomes between them.

Primary outcomes

changes in ocular alignment

Time frame: at one month, 6 month and one year postoperatively.

Detect ocular alignment by using Krimsky test to measure angle of deviation in prism diopter

Study contacts

Contact information is provided by the study sponsor or research team.

Alahmady Hamad Alsaman, Professor

CONTACT

+201111102698

sara ahmed abdelraheem, Assistant lecturer

CONTACT

[email protected]

+201153987387

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

A Comparative Study Between Three Surgical Techniques in Large Angle Exotropia: Bilateral Lateral Rectus Recession With Medial Rectus Resection, Bilateral Medial Rectus Resection and Resection-Transplantation

Important dates

Study start: 2025
Primary completion: 2027
Study completion: 2027
First posted: Aug 27, 2025
Registry last updated: Aug 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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