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OpenTrials
Completed

NCT Number: NCT02474043

A Community-based, Behavioral Intervention to Improve Screening for Hepatitis C Among High-risk Young Adults in Wisconsin

The goal of this study is to evaluate the effectiveness of a brief, computerized behavioral intervention for promoting screening for hepatitis C and reducing risky behavior for people who inject drugs (PWID).

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Key information

About this study

People who inject drugs (PWID) are at high risk for hepatitis C virus (HCV) infection if they share contaminated injection equipment with others. Many are infected but are unaware of it, making it likely they will transmit the virus to others if they share contaminated injecting equipment. Problems related to hepatitis C can be avoided if people know their status by getting tested and referred to treatment.

In this study, the investigators will recruit eligible PWID in several cities in Wisconsin using a social networks strategy, in which clients who receive services at a syringe exchange program are asked to refer peers who also inject drugs to participate in the study. All participants will undergo a baseline computerized risk assessment that elicits information about hepatitis C status, previous testing, transmission risk behaviors, and overdose risk. Participants will then be randomly-assigned to receive either standard risk reduction counseling from a prevention specialist, or computerized tailored risk reduction messages that are specific to their reported risk behaviors, attitudes and beliefs. A follow-up assessment will be completed after 3 months to evaluate changes in behavioral risk and intention to undergo HCV screening. A database will be searched to determine which participants returned for HCV screening within 12 months of enrollment, and of those, which ones tested positive for HCV.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 or over
  • English-speaking
  • Reports injection of illicit drugs in the past month

Exclusion criteria

  • Unable to provide informed consent due to cognitive impairment
  • Unwilling to provide personal locator information and consent to be contacted for follow-up after 3 months.
  • Currently known to be pregnant

Treatment and study plan

Hep-Net Intervention

Behavioral

The Hep-Net Intervention is a web-based questionnaire and tailored feedback system designed to increase readiness to change with respect to several behaviors. The behaviors include (1) reducing or quitting drug use; (2) using sterile equipment every time one injects drugs; (3) undergoing screening for hepatitis C; (4) receiving training to use naloxone to prevent death due to opioid overdose.

Usual Care

Behavioral

Clients receive health education and risk reduction counseling from a trained prevention specialist.

Primary outcomes

  1. Screening for hepatitis C infection

    Time frame: 12 months

    Participants will be followed for 12 months to determine whether they undergo repeated screening for hepatitis C

Sponsors and collaborators

Lead sponsor

University of Wisconsin, Madison

Other

Collaborators

  • AIDS Resource Center of Wisconsin

Registry information

Acronym: Hep-Net

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
Jun 17, 2015
Registry last updated
Jan 11, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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