Skip to main content
OpenTrials
Completed

NCT Number: NCT01962038

A Combined Training Program for Veterans With Amnestic Mild Cognitive Impairment

The purpose of this study is examine the efficacy of a combination physical exercise and cognitive training program on improving memory in older Veterans with amnestic Mild Cognitive Impairment.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Amnestic Mild Cognitive Impairment Cognition Disorders Cognitive Dysfunction Mental Disorders Neurocognitive Disorders

Age range

50 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

VA Palo Alto Health Care System

Palo Alto, California, 94304, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • diagnosis of amnestic Mild Cognitive Impairment
  • available informant
  • visual and auditory acuity to allow neuropsychological testing
  • willingness to participate in exercise training + cognitive training for 8 months
  • approval of primary provider to participate in exercise trial

Exclusion criteria

  • current severe psychiatric disorder
  • diagnosis of dementia
  • history of neurological or system illness affecting CNS function
  • acute illness or unstable chronic illness
  • current severe cardiac disease
  • inability to exercise consistently because of orthopedic or musculoskeletal problems
  • morbid obesity
  • inability to read, verbalize understanding and voluntarily sign the informed consent

Treatment and study plan

Combined Aerobic and Resistance Exercise

Behavioral

Gym and home based aerobic and resistance exercises

stretching exercises

Behavioral

Gym and home based stretching exercises

Cognitive training

Behavioral

Group-based cognitive training

Primary outcomes

  1. Change from Baseline to 28 weeks in delayed recall of a word list

    Time frame: Baseline, 24 weeks, 28 weeks

  2. Change from Baseline to 28 weeks in Delayed Recall of Names-Face Task

    Time frame: Baseline, 24 weeks, 28 weeks

Secondary outcomes

  1. Non-Cognitive Outcomes (Depression, Sleep, Quality of Life)

    Time frame: Baseline, Time 2, Time 3

Other outcomes

  1. Exercise Assessment

    Time frame: Baseline, Time 2, and Time 3

Sponsors and collaborators

Lead sponsor

Palo Alto Veterans Institute for Research

Other

Collaborators

  • U.S. Army Medical Research and Development Command

Registry information

Important dates

Study start
2013
Primary completion
2017
Study completion
2017
First posted
Oct 14, 2013
Registry last updated
Apr 5, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.