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Active, Not Recruiting

NCT Number: NCT05719116

A Combined Aerobic and Resistance Training Program for Adults With Psychotic Disorders

The study is a feasibility study of a combined high intensity aerobic and strenght exercise program for persons with psychotic disorders. The feasibility of the protocol will be investigated, in addition to the participants subjective experience with the participation.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Psychosis Mental Disorders Psychotic Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Solli DPS

Bergen, Nesttun, 5228, Norway

About this study

The aim of this study is to investigate the feasibility of a 16 week physical exercise intervention combining strenght and aerobic training in group for patients with psychotic disorders. In addition, the feasibility of the test protocol and participants subjective experience with the intervention will be investigated.

Research shows positive effects of physical exercise for patients with psychotic disorders regarding maximal aerob training, maximal muscle strength, physical, cognitive and social functioning, and symptom levels. Effects and the degree of feasibility of physical exercise for patients with psychotic disorders are amplified by regarding their preferences and needs, and if they experience support and guidance during the intervention. Earlier studies have focused mostly on either strength og endurance training, or combined interventions of moderate intensity. We now want to investigate the feasibility of an invidually adjusted combined program of high intensity.

After the intervention, participants will be interviewed about their experience with participating.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Participants with psychotic disorder:

Inclusion criteria

  • Signed informed consent
  • Diagnosed with psychotic disorder
  • Physically able to participate in physical exercise
  • Is a patient at Solli DPS
  • Motivated for participating in physical exercise

Exclusion criteria

  • Physical conditions precluding the participant from the physical testing/training
  • Mental state that hinders participation, such as ongoing suicidality, substance abuse or brain organic disorder

Participants with psychiatric disorder, but no psychotic disorder:

Inclusion criteria

  • Signed informed consent
  • Diagnosed with psychiatric disorder, but not a psychotic disorder
  • Physically able to participate in physical exercise
  • Is a patient at Solli DPS
  • Motivated for participating in physical exercise

Exclusion criteria

  • Physical conditions precluding the participant from the physical testing/training
  • Mental state that hinders participation, such as ongoing suicidality, substance abuse or brain organic disorder

Treatment and study plan

Physical exercise

Behavioral

The physical exercise will be aerobic and strength training. The sessions will last app. 1 hour.

Primary outcomes

  1. Feasibility of the intervention program

    Time frame: After 16 weeks of intervention

    How many participants completed the physical training intervention.

Secondary outcomes

  1. Aerobic capasity: Ekblom Bak submaximal ergometer cycle test

    Time frame: At week 0 and 16

    Estimating Vo2max

  2. Aerobic capasity: 4 x 4 interval for estimating VO2max

    Time frame: At week 0 and 16

    Standarised 4x4 interval training for estimating VO2max with the smartphone app My Workout GO

  3. Strength: 1 RM test of bench press

    Time frame: At week 0 and 16

    Maximal test of strenght of upper body

  4. Strenght: 1 RM test of squat

    Time frame: At week 0 and 16

    Maximal test of lower body musculature

  5. Psychotic symptoms: The Positive and Negative Syndrome Scale

    Time frame: At week 0 and 16

    For the participants with psychotic disorders only. A measure of positive and negative psychotic symptoms. Each item is scored on a scale from 1-7 with a higher score indicating higher symptom level.

  6. Depression symptoms: The Calgary Depression Scale for Schizophrenia

    Time frame: At week 0 and 16

    A measure of depressive symptoms. Each item is scored on a scale from 0-3 with a higher score indicating higher symptom level.

  7. Anxiety symptoms: GAD-7

    Time frame: At week 0 and 16

    A measure of anxiety symptoms. This is a 7-item self-report questionnaire where participants rate on a scale from 0 (not at all sure) to 3 (nearly every day). A higher score indicates greater symptom severity.

  8. Quality of life: SF-12

    Time frame: At week 0 and 16

    A measure of health related quality of life. The items is scored after variying categories such as "yes" and "no", and "How much time during the past 4 weeks...".

Other outcomes

  1. In depth interview

    Time frame: After 16 weeks of intervention

    A semi structured interview for asking the participants about their experience with the intervention

Sponsors and collaborators

Lead sponsor

Solli Distriktspsykiatriske Senter

Other

Registry information

Acronym: TREPP

Important dates

Study start
2022
Primary completion
2026
Study completion
2028
First posted
Feb 8, 2023
Registry last updated
Sep 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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