A Clinical Trial to Assess the Pharmacokinetics and Safety of AD-229 Compared to AD-2291 in Healthy Adults

The study compare and evaluate the safety and pharmacokinetic characteristics between the administration of AD-229 and the administration of AD-2291 in healthy adults.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Gastritis Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Stomach Diseases

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Body mass index (BMI) between 18.5 kg/m2 and 29.9 kg/m2 at the time of screening visit
The Age equal to or greater than 19 in healthy volunteers at the time of screening visit

Exclusion criteria

Participation in another clinical study with an investigational drug within the 6 months from scheduled first administration
Other exclusions applied

Treatment and study plan

AD-229

Drug

AD-229 Oral Tablet

AD-2291

Drug

AD-2291 Oral Tablet

Primary outcomes

Maximum concentration of drug in plasma (Cmax)

Time frame: pre-dose (0hour) to 72hours

Cmax of AD-229
Area under the plasma concentration-time curve during dosing interval (AUCt)

Time frame: pre-dose (0hour) to 72hours

AUCt of AD-229

Sponsors and collaborators

Lead sponsor

Addpharma Inc.

Industry

Registry information

Official study title

An Open-label, Randomized, 2-treatment, 2-sequence, 2-period, Crossover Study to Evaluate the Pharmacokinetics and Safety Between the Administration of AD-229 and the Administration of AD-2291 for Healthy Adults in Fasting State

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Feb 4, 2026
Registry last updated: Feb 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Not Yet Recruiting