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NCT Number: NCT07252206

A Case Series of Culturally-adapted CBTp for Black People in the UK

The goal of this case series study is to learn if culturally-adapted cognitive-behavioural therapy is practical, acceptable and safe among Black Sub-Saharan African and Caribbean people experiencing psychosis. The main question it aims to answer is:

Is culturally-adapted CBT for psychosis feasible, acceptable to and safe for Black Sub-Saharan African and Caribbean people experiencing psychosis?

Participants will be asked to:

* Answer some questionnaires about how things are at the moment * Attend up to 16 sessions of therapy * Answer the same questionnaires to see what has changed, if anything * Complete a semi-structured interview about their expectations and experience of therapy

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Key information

Conditions

Psychosis Mental Disorders Psychotic Disorders Schizophrenia Spectrum Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

16 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Greater Manchester Mental Health NHS Foundation Trust

Manchester, United Kingdom

Location status: Recruiting

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Service users who identify as Black British, Black Caribbean, Black African, African-Caribbean or Mixed African/Caribbean with at least one parent and/or grandparent born in a Sub-Saharan African or Caribbean country
  • People with a current ICD-10 schizophrenia spectrum disorder diagnosis, or who are currently receiving or have received support from an Early Intervention in Psychosis team
  • 16 years or older
  • Sufficient understanding of English to complete study measures and engage with CBTp

Exclusion criteria

  • Current, primary diagnosis of substance use disorder
  • Organic aetiology of psychosis
  • Lacking capacity to provide full informed consent
  • Currently experiencing a mental health crisis (i.e., are open to a home-based treatment team; are currently under Section of the Mental Health Act or have been under Section in the past 3 months) or immediate high risk to self or others (i.e., current suicidal intent or plans; unmanaged and intense non-suicidal self-injury)
  • Currently receiving CBTp or received CBTp within the preceding 3 months
  • Unwilling to participate in culturally-adapted CBTp

Treatment and study plan

Culturally-adapted cognitive-behavioural therapy

Behavioral

Cognitive-behavioural therapy for psychosis culturally-adapted for Black Sub-Saharan African and Caribbean people using a dedicated, integrated treatment manual

Primary outcomes

  1. Semi-structured qualitative interview: Service user acceptability

    Time frame: End of therapy (16 weeks)

    Service user satisfaction as assessed by qualitative interview.

Secondary outcomes

  1. Working Alliance Inventory-Short Form Revised

    Time frame: End of therapy (16 weeks)

    Acceptability measured sessionally using the Working Alliance Inventory-Short Form Revised (Hatcher & Gillaspy, 2006)

  2. Adverse Events Checklist

    Time frame: Each therapy session (16 weeks)

    Safety monitored sessionally using an Adverse Events Checklist developed for this study

  3. Subjective Experience of Psychosis Scale

    Time frame: End of therapy (16 weeks)

    Subjective distress measured by the Subjective Experience of Psychosis Scale (Haddock et al., 2011)

  4. Questionnaire about the Process of Recovery

    Time frame: End of therapy (16 weeks)

    Perceived recovery measured by the Questionnaire about the Process of Recovery (Law et al., 2014)

  5. Depression, Anxiety and Stress Scales

    Time frame: End of therapy (16 weeks)

    Emotional wellbeing measured by the Depression, Anxiety and Stress Scales (Lovibond & Lovibond, 1995)

Study contacts

Contact information is provided by the study sponsor or research team.

Peter Panayi

CONTACT

[email protected]

+44161 306 6000

Sponsors and collaborators

Lead sponsor

University of Manchester

Other

Registry information

Official study title

Culturally-adapted Cognitive-behavioural Therapy for Black Sub-Saharan African and Caribbean People Experiencing Psychosis: A Case Series

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Nov 26, 2025
Registry last updated
Jul 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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