Center for Learning and Health, Johns Hopkins Bayview Medical Campus, 5200 Eastern Ave., Suite W142
Baltimore, Maryland, 21224, United States
NCT Number: NCT01416584
The purpose of this study is to evaluate the effectiveness of the Therapeutic Workplace in promoting methadone treatment and increasing abstinence in unemployed, out-of-treatment injection heroine users.
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Notify Me18 year–65 year
All sexes
Interventional
Not applicable
Baltimore, Maryland, 21224, United States
A randomized study is planned for 5 years to evaluate the effectiveness of the Therapeutic Workplace in promoting methadone treatment and abstinence in unemployed injection drug users. Participants will be recruited through street outreach, at agencies that serve the target populations, and informal word-of-mouth referrals. Participants will be invited to attend the workplace and to enroll in the methadone treatment. To engage participants in the workplace, they will be allowed to work independent of whether they enroll in methadone treatment and independent of their drug use. The workplace participants (N=162) will be randomly assigned to three groups. The "Usual Care Control" participants will be allowed to work independent of their methadone use or urinalysis results. The "Methadone Contingency" participants will be required to take methadone to attend work, and will receive a brief pay decrease for failing to take their medication. The "Methadone & Abstinence Contingency" participants will be required to take their medication in order to attend work, as well as receive a brief pay decrease for any positive urine samples for both cocaine and methadone.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Individuals were eligible if they were:
Participants were excluded if they
Eligible participants were invited to participate in a 4-week induction. Participants who attended the workplace for at least five minutes on two out of five workdays in the last week of induction were randomly assigned to one of three conditions and were invited to attend the workplace for an additional 26 weeks
Participants had to enroll in methadone treatment and take daily doses of methadone to gain access to the workplace.
Participants had to enroll in methadone treatment and take daily doses of methadone to gain access to the workplace and they had to provide opiate and cocaine negative urine samples to maintain the maximum pay.
Time frame: 6 months
The percentage of months in which participants were enrolled in methadone treatment during the 6-month intervention evaluation period?
Time frame: 6 months
Percentage of urine sample negative for opiates at each of the six 30-day assessments scheduled throughout the intervention evaluation
Time frame: 6 months
Was the participant's urine sample negative for cocaine at each of the six 30-day assessments scheduled throughout the intervention evaluation period?
Time frame: 6 months
Was each participant's urine sample negative for cocaine at each of the Monday, Wednesday, Friday urine samples scheduled throughout the intervention evaluation period?
Time frame: 6 months
Was each participant's urine sample negative for opiates at each of the Monday, Wednesday, Friday urine samples scheduled throughout the intervention evaluation period?
Time frame: 6 months
Percent of months that participants reported sharing needles or works.
Time frame: 6 months
The percent of months that participants reported going to a shooting gallery/hour or other place where users go to shoot-up.
Time frame: 6 months
Percent of months that participants reported injecting drugs.
Time frame: 6 months
Was each participant in methadone treatment at the end of the 6-month intervention evaluation period?
Time frame: 6 months
Did the participant enter methadone treatment at any point in the 6-month treatment period?
Johns Hopkins University
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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