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NCT Number: NCT07838935

Effectiveness of High-Intensity Laser Therapy in Patients With Greater Trochanteric Pain Syndrome

Greater trochanteric pain syndrome causes pain on the outer side of the hip. This study examined whether adding high-intensity laser therapy to exercise improved hip pain and function more than exercise alone.

Adults with this condition were randomly assigned to two groups. Both groups followed the same exercise program three days per week for 8 weeks. One group also received high-intensity laser therapy twice weekly for 4 weeks, for a total of eight sessions. Each laser session lasted 15 minutes.

The main outcome was the total Harris Hip Score, which assesses hip pain and function. Pain intensity and quality of life were also assessed. Evaluations took place before treatment, 1 month after treatment initiation, and 3 months after completion of the 8-week exercise program.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Usak University Faculty of Medicine

Uşak, Turkey (Türkiye)

About this study

This single-center, randomized controlled trial was conducted at the Physical Medicine and Rehabilitation Clinic of Uşak Training and Research Hospital. Participants had lateral hip pain lasting at least 3 months. The diagnosis was based on clinical examination and supported by magnetic resonance imaging.

Participants were assigned to exercise alone or high-intensity laser therapy plus exercise using a computer-generated random number list. The trial was open-label. Participants, the treating physiotherapist, and the physician performing the assessments knew the treatment assignments. No sham laser treatment was used.

The exercise program included gluteal muscle activation, hip abductor strengthening, pelvic stabilization, stretching, and functional exercises. A physician taught the exercises. Participants were instructed to perform three sets of 10 repetitions for each exercise. Exercise intensity and progression were adjusted to pain tolerance and functional capacity. Adherence was monitored through weekly telephone calls.

An experienced physiotherapist applied laser treatment around the greater trochanter and the gluteus medius and minimus tendon insertions. Both the participant and the physiotherapist wore protective eyewear. Participants were monitored for adverse events during and after treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 18 years or older. Clinical diagnosis of greater trochanteric pain syndrome supported by magnetic resonance imaging.

Lateral hip pain for at least 3 months, with tenderness over the greater trochanter and pain provoked by hip abduction.

Baseline Visual Analog Scale pain score of at least 4 out of 10. Ability to understand and complete the assessment forms. No regular participation in sports during the previous 6 months. Provision of written informed consent.

Exclusion criteria

Previous surgery on the affected hip or advanced hip osteoarthritis. Lumbar radiculopathy or a neurological disease affecting lower limb function. History of inflammatory rheumatic disease. Active infection or malignancy. Corticosteroid injection in the trochanteric region within the previous 3 months.

Physical therapy or rehabilitation for the same condition within the previous 3 months.

Pregnancy. Any contraindication to high-intensity laser therapy. Inability to follow the treatment or follow-up protocol.

Treatment and study plan

Exercise Program

Behavioral

Participants performed a standardized hip exercise program three days per week for 8 weeks. A physician taught the exercises. The program included gluteal muscle activation, hip abductor strengthening, pelvic stabilization, stretching, and functional closed kinetic chain exercises. Exercise intensity and progression were adjusted to each participant's pain tolerance and functional capacity. Adherence was monitored through weekly telephone calls.

High-intensity laser therapy

Device

High-intensity laser therapy will be applied to the greater trochanteric region and the painful insertion sites of the gluteus medius and gluteus minimus tendons twice weekly for 4 weeks, for a total of 8 treatment sessions, according to the study treatment protocol. Both the participant and the therapist will wear protective eyewear during each treatment session.

Primary outcomes

  1. Total Harris Hip Score (HHS)

    Time frame: Baseline, 1 month after treatment initiation, and 3 months after completion of the 8-week exercise program.

    Hip pain and function were assessed using the Harris Hip Score (HHS). The score includes pain, function, deformity, and range of motion. Total scores range from 0 to 100, with higher scores indicating better hip status. The total HHS was the primary outcome measure.

Secondary outcomes

  1. Pain intensity measured by the Visual Analog Scale (VAS)

    Time frame: Baseline, 1 month after treatment initiation, and 3 months after completion of the 8-week exercise program.

    Lateral hip pain during daily activities was assessed using a 10-cm Visual Analog Scale (VAS). Scores range from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Lower scores indicate less pain.

  2. SF-36

    Time frame: Baseline, 1 month after treatment initiation, and 3 months after completion of the 8-week exercise program.

    Health-related quality of life will be assessed using the Short Form-36 (SF-36) questionnaire. The SF-36 evaluates eight domains of health, including physical functioning, role limitations due to physical health, role limitations due to emotional problems, vitality, mental health, social functioning, bodily pain, and general health. Higher scores indicate better health-related quality of life. In this study, the SF-36 will be used as a secondary outcome measure to evaluate changes in health-related quality of life.

Interested in participating?

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Sponsors and collaborators

Lead sponsor

Uşak University

Other

Registry information

Official study title

Investigation of the Effectiveness of High-Intensity Laser Therapy in Patients Diagnosed With Greater Trochanteric Pain Syndrome: A Prospective Randomized Controlled Trial

Acronym: HILT-GTPS

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Sep 24, 2026
Registry last updated
Sep 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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