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NCT Number: NCT07838584

Comparison of Ischemic Release and Sustained Pressure Direct Myofascial Release in Upper Trapezius Trigger Point

This randomized controlled trial aims to compare the clinical effectiveness of ischemic release and sustained pressure direct myofascial release for upper trapezius trigger points.

The study will compare their effects on pain pressure threshold, cervical range of motion, and scapular upward rotation following a two-week intervention.

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Key information

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Foundation University College of Physical Therapy

Islamabad, Punjab Province, 44000, Pakistan

Location status: Recruiting

Location contact

Quratulain Saeed, MS-OMPT

CONTACT

[email protected]

+92331 5562889

About this study

Eligible participants will be recruited through purposive sampling. Upper trapezius trigger points will be assessed by manual palpation to identify a taut band and hypersensitive nodule, followed by pressure to determine reproduction of the participant's familiar pain. Baseline assessments will include pain pressure threshold, cervical range of motion, and scapular upward rotation. After baseline assessment, 42 participants will be allocated randomly into respective groups, each having 21 participants.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • AGE; 18-35 years
  • Male & Female
  • Unilateral Trapezius muscle involvement
  • Presence of at least one active trigger point in upper trapezius muscle.
  • Numeric Pain Rating Scale (NPRS) score of 3-8 points
  • Subacute Neck pain for 4-12 weeks
  • Point tenderness on palpable taut band
  • Reproducible provocation according to referred pain pattern mapping
  • Cervical range of motion change in SB ≥ 2° and ROT ≥ 2° than normal SB=45° AND ROT=70°
  • Willing to participate and provide informed consent

Exclusion criteria

  • Serious pathology (e.g. neoplasm, fracture)
  • Radiculopathy
  • History of whiplash injury within past 6 months
  • Neurological deficit
  • Taking steroids or on concurrent physiotherapy treatment
  • Prior surgery to cervical spine & shoulder

Treatment and study plan

Ischemic release

Procedure

Participants will receive a two-week physiotherapy program with three sessions per week. Each session will include heat application followed active ROM and passive stretching.

Participants in Group A will receive ischemic compression in addition to standard physiotherapy. Pressure should be applied via thumb for 20 second - 1 minute until pain decreases or muscle begin to relax.

Other names: Ischemic compression

Sustained pressure Direct Myofascial release

Procedure

Participants will receive a two-week physiotherapy program with three sessions per week. Each session will include heat application followed active ROM and passive stretching. Participants in Group B will receive sustained pressure direct MFR in addition to standard physiotherapy. Apply pressure to the trigger point for 8-20 seconds, maintaining it until a physical "discharge" or release is felt, which may take five minutes or more.

Primary outcomes

  1. Pain Pressure Threshold

    Time frame: Baseline and after 2 weeks.

    Pain pressure threshold will be assessed using a Wagner digital algometer.

  2. Cervical range of motion

    Time frame: Baseline and after 2 weeks

    Cervical ROM will be assessed using a goniometer.

  3. Scapular upward rotation

    Time frame: Baseline and after 2 weeks

    Scapular upward rotation will be assessed using a bubble inclinometer.

Study contacts

Contact information is provided by the study sponsor or research team.

Quratulain Saeed, MS-OMPT

CONTACT

[email protected]

+92331 5562889

Sohaima Javed, DPT

CONTACT

[email protected]

+92321 5404044

Sponsors and collaborators

Lead sponsor

Foundation University Islamabad

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Sep 24, 2026
Registry last updated
Sep 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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