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NCT Number: NCT07837687

Effect of Paraffin Wax on Joint Contractures

Limited studies have objectively evaluated the benefit on skin pliability, and relieving itch and pain of paraffin wax, nor has paraffin wax treatment been compared to mineral oil, which is an ingredient in therapeutic paraffin wax. The objective of this study is to examine the immediate impact after paraffin treatment compared with mineral oil controls on joint passive range of motion.

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Key information

Age range

16 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

The development of joint contractures after a burn injury represents one of the most important morbidities leading to reduced function and quality of life. Paraffin wax is commonly applied to contracted joints for its proposed benefits of increasing skin pliability, and/or relieving itch and pain. This pilot study will determine the feasibility of performing a fully powered study to objectively evaluate whether paraffin wax therapy significantly improves PROM in adult burn survivors with joint contractures of greater than 15% normal joint ROM (upper or lower extremity) compared to equivalent mineral oil treated joint contractures. This study will characterize the changes in PROM, AROM, itch, and pain in adult burn survivors immediately after the application of paraffin wax treatment relative to an intra-individual control scar treated with mineral oil. This will be a prospective, evaluator-blinded, intra-individual, randomized, controlled, pre-post pilot study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult burn survivors (16 years and older)
  • Have joint contractures ≥15% normal PROM at two different joints directly related to their burn injury/scars
  • Are proficient in English and/or French
  • Provide informed consent

Exclusion criteria

  • Patients who have a cognitive/psychiatric condition that could impair their understanding of the consent process or adherence to protocol procedures
  • Patients with neurological impairments related to their burn injury, such as a drop foot or a drop wrist
  • Patients with pre-burn joint pathology that limited their PROM

Treatment and study plan

Paraffin wax

Other

Application of Paraffin wax on joint contracture for 20 mins before removal

Mineral Oil

Other

Application of Mineral oil on joint contracture for 20 mins before removal

Primary outcomes

  1. PROM changes

    Time frame: 20 minutes (enrollment to end of visit)

    Passive range of motion of joint contractures treated with Paraffin wax or Mineral oil, before and after treatment, following regular and revised scar goniometry in extension and flexion

Secondary outcomes

  1. AROM changes

    Time frame: 20 minutes (enrollment to end of visit)

    active range of motion of joint contractures treated with paraffin wax or mineral oil, before and after treatment, following regular and revised scar goniometry in extension and flexion

  2. Pain changes in joint contractures

    Time frame: 20 minutes (enrollment to end of visit)

    Subjective pain of joint contractures treated with paraffin wax or mineral oil (before and after) with Visual analog thermometer

  3. Itch changes in joint contractures

    Time frame: 20 minutes (enrollment to end of visit)

    Subjective itch of joint contractures treated with paraffin wax or mineral oil (before and after) with Visual analog thermometer

Interested in participating?

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Sponsors and collaborators

Lead sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Other

Registry information

Official study title

Effects of Paraffin Wax Therapy on Passive Range of Motion Post-burn Injury: a Pilot Randomized Control Trial

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Sep 23, 2026
Registry last updated
Sep 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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