Skip to main content
OpenTrials
Completed

NCT Number: NCT07837167

The Effect of Platelet Rich Plasma Injection on Post Internal Urethrotomy Stricture Recurrence

The effect of platelet rich plasma injection on post internal urethrotomy stricture recurrence

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Stricture Urethra Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Male Urogenital Diseases Urethral Diseases Urethral Obstruction Urethral Stricture Urogenital Diseases Urologic Diseases

Age range

20 year–50 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 3

Primary location

Mostafa Ali Mahmoud

Banhā, Qalyubia Governorate, 13111, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with symptomatic bulbar urethral stricture (diagnosed by retrograde urethrography) aged between 20 and 50 years.

Exclusion criteria

  • History or medical evidence of symptomatic benign prostatic enlargement.
  • documented or suspicious prostate cancer.
  • history of hypospadias, neurogenic disorders.
  • previous internal urethrotomy or urethral reconstruction.
  • strictures longer than 1.5 cm.
  • multiple strictures.

Treatment and study plan

PRP injection

Drug

The effect of platelet rich plasma injection on post internal urethrotomy stricture recurrence

VIU

Procedure

VIU in stricture urethra

Primary outcomes

  1. Post-voiding residual urine volume (PVR)

    Time frame: 2 weeks

    Post-voiding residual urine volume will be measured by ultrasonography , Unit of Measure : ml .

  2. Maximum urinary flow rate (Qmax)

    Time frame: 2 weeks

    Maximum urinary flow rate will be assessed by uroflowmetry , Unit of Measure : ml/second

Secondary outcomes

  1. recurrence of stricture urethra

    Time frame: 2 years

    recurrence of stricture urethra measured by ascending urethrogram and uroflowmetry

Interested in participating?

Completed

Looking for future studies?

Notify Me

Sponsors and collaborators

Lead sponsor

Benha University

Other

Registry information

Acronym: prp vs VIU

Important dates

Study start
2024
Primary completion
2025
Study completion
2026
First posted
Sep 23, 2026
Registry last updated
Sep 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.