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NCT Number: NCT07832994

Metaboic Syndrome and Fatty Liver in Celiac Disease Females: Reponse to Exercise in Adolescents

metabolic syndrome and fatty liver is common in adolescents with celiac diseases. exercise may control these cardiovascular risk factors

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Key information

Conditions

Celiac Disease Digestive System Diseases Fatty Liver Gastrointestinal Diseases Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Intestinal Diseases Liver Diseases Malabsorption Syndromes Metabolic Diseases Metabolic Syndrome Non Alcoholic Fatty Liver Non-alcoholic Fatty Liver Disease Nutritional and Metabolic Diseases

Age range

13 year–17 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

About this study

forty metabolic syndrome and fatty liver female adolescents with celiac diseases will assigned to exercise group or control group. the group will contain twenty patients. control group will be wait list. exercise group will perform 40 minutes of walking on a treadmill three times weekly for three months.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • celiac disease
  • metabolic syndrome
  • nonalcholic fatty liver

Exclusion criteria

  • cardiac disease
  • renal failure
  • respiratory disease

Treatment and study plan

Walking exercise

Behavioral

twenty metabolic syndrome and fatty liver female adolescents with celiac diseases will will perform 40 minutes of walking on a treadmill three times weekly for three months.

Primary outcomes

  1. alanine transamianse

    Time frame: It will be measured after 12 weeks

    It will be asssessed in plasma

Secondary outcomes

  1. Asparate tranamianse

    Time frame: It will be measured after 12 weeks

    it will be assessed in plasma

  2. gamma glutamyl transferase

    Time frame: it will be measured after 12 weeks

    it will be assessed in plasma

  3. alkaline phosphatase

    Time frame: it will be measured after 12 weeks

    it will be assessed in plasma

  4. Body mass index

    Time frame: it will be assessed after 12 weeks

    it wil be measured with empty stomach and bladder

  5. wasit circumference

    Time frame: it will be assessed after 12 weeks

    it will be assessed at the level of umbilicus

  6. systolic blood pressure

    Time frame: it will be assessed after 12 weeks

    it will be assessed at level of brachial artery

  7. diastolic blood pressure

    Time frame: it will be assessed after 12 weeks

    it will be assessed at level of brachial artery

  8. blood glucose

    Time frame: it will be assessed after 12 weeks

    it will be measured in fasting status in blood

  9. high density lipoproteins

    Time frame: it will be assessed after 12 weeks

    it will be assessed in plasma

  10. triglycerides

    Time frame: it will be assessed after 12 weeks

    it will be assessed in plasma

Study contacts

Contact information is provided by the study sponsor or research team.

Ali MA Ismail, PhD

CONTACT

[email protected]

+201005154209

Fatma mohamed, PhD

CONTACT

[email protected]

+201033321109

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Sep 22, 2026
Registry last updated
Sep 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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