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Completed

NCT Number: NCT07831070

Does the Combination of Cervical and Sacroiliac Mobilization Enhance Clinical Outcomes in Cervical Radiculopathy?

This study evaluated whether adding mobilization and myofascial techniques targeting the lumbar and sacroiliac regions to cervical-focused manual therapy provides additional clinical benefits in individuals with cervical radiculopathy. Changes in pain, disability, cervical range of motion, and sacroiliac joint (SIJ) clinical findings were assessed. The study also examined whether changes in SIJ clinical findings were associated with changes in cervical clinical outcomes, thereby exploring the relationship between cervical and lumbopelvic responses to an extended regional manual therapy approach.

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Key information

Conditions

Cervical Radiculopathy Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Radiculopathy

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Fenerbahce University

Ataşehir, Istanbul, 34758, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

The diagnosis of cervical radiculopathy was established by a specialist neurosurgeon based on clinical examination and magnetic resonance imaging (MRI) findings. Individuals aged 18-55 years with a confirmed diagnosis of cervical radiculopathy and who were considered clinically appropriate for manual therapy were screened for eligibility -

Exclusion criteria

criteria were previous cervical spine surgery; rheumatologic, vestibular, neurological, or cardiopulmonary disorders that could interfere with assessment or treatment; limb-length discrepancy; scoliosis; a history of fracture involving the spine, sacroiliac joint (SIJ), or lower extremities; mechanical low back pain; receipt of exercise-based treatment or physical therapy within the preceding 6 months; and pregnancy

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Treatment and study plan

Cervical manual-focused manual therapy

Other

Manual therapy targeting the cervical region was administered to individuals with cervical radiculopathy. The intervention consisted of cervical-focused manual therapy techniques aimed at addressing pain, mobility limitations, and clinical symptoms associated with cervical radiculopathy. All interventions were delivered by the same clinician with 21 years of clinical experience in manual therapy.

Extended Regional Manual Therapy

Other

Additional manual therapy targeting the lumbar and sacroiliac regions was administered in combination with cervical-focused manual therapy. The intervention included mobilization and myofascial techniques directed at the lumbar and sacroiliac regions. This extended regional approach was designed to evaluate whether treatment beyond the cervical region provides additional effects on cervical clinical outcomes and sacroiliac joint clinical findings. All interventions were delivered by the same clinician with 21 years of clinical experience in manual therapy.

Primary outcomes

  1. Cervical Radiculopathy Impact Scale (CRIS)

    Time frame: Baseline and immediately after the intervention

    Cervical Radiculopathy Impact Scale (CRIS)

  2. Neck Disability Index (NDI)

    Time frame: Baseline and immediately after completion of the intervention protocol

    Neck-related disability will be assessed using the Neck Disability Index (NDI), a 10-item self-reported questionnaire. The total score ranges from 0 to 50, with higher scores indicating greater neck-related disability. The validated Turkish version will be used.

  3. Short-Form McGill Pain Questionnaire (SF-MPQ)

    Time frame: Baseline and immediately after completion of the intervention protocol

    Pain will be assessed using the Short-Form McGill Pain Questionnaire (SF-MPQ). The questionnaire includes 15 pain descriptors comprising 11 sensory and 4 affective items. Each descriptor is rated from 0 (none) to 3 (severe), with higher scores indicating greater pain severity. The validated Turkish version will be used.

  4. Active Cervical Flexion Range of Motion

    Time frame: Baseline and immediately after completion of the intervention protocol

    Active cervical flexion range of motion will be measured in degrees using a Baseline® digital goniometer. Participants will actively move through their available cervical flexion range using standardized positioning and anatomical landmarks. Higher values indicate greater cervical flexion range of motion.

Sponsors and collaborators

Lead sponsor

Fenerbahce University

Other

Collaborators

  • Istinye University

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Sep 21, 2026
Registry last updated
Sep 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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