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OpenTrials
Completed

NCT Number: NCT07828990

Cardiovascular Risk Factors and Lipid Profile in Hospitalized Mexican Adults

Traditional cardiovascular risk models are limited in capturing functional alterations in HDL-C linked to smoking and diet in Latin American populations. We analyzed the relationship between traditional and non-traditional risk factors and the serum lipid profile of hospitalized Mexican adults, emphasizing HDL-C behavior.

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Key information

Conditions

Dyslipidemia Behavior Dyslipidemias Lipid Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases Smoking

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hospital General "Dr. Salvador Zubirán Anchondo"

Chihuahua City, Chihuahua, 31000, Mexico

About this study

An analytical, cross-sectional study was conducted in 70 adults following the STROBE statement. Non-parametric tests, Huber's robust multiple regression, and structural equation modeling (SEM) were performed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Men and women over 18 years of age who are capable of deciding wheter to participate in the study or not.

Exclusion criteria

  • Men and women under 18 years of age, or men and women over 18 years of age who are already under pharmacologic lipid-lowering treatment of any kind.

Treatment and study plan

Primary outcomes

  1. Measure serum lipid profile (total cholesterol, HDL-C, LDL-C, triglycerides, VLDL-C)

    Time frame: Baseline

    Differences in serum lipid concentrations (mg/dL) according to traditional and non-traditional cardiovascular risk factors, with emphasis on HDL-C as an indirect marker of antiatherogenic dysfunction

Secondary outcomes

  1. Measure HDL-C concentration by smoking status

    Time frame: Baseline

    Comparison of HDL-C levels between active smokers and non-smokers

  2. Measure Triglyceride and VLDL-C levels in patients with diabetes mellitus

    Time frame: Baseline

    Comparison of triglyceride and VLDL-C concentrations by diabetes mellitus diagnosis

  3. Measure HDL-C levels by ultraprocessed beverage consumption

    Time frame: Baseline

    Association between self-reported ultraprocessed beverage intake and HDL-C concentration

  4. Identify anthropometric predictors of lipid profile

    Time frame: Baseline

    Contribution of weight, height, and BMI to each lipid variable via multiple regression and structural equation models

Sponsors and collaborators

Lead sponsor

Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo

Other Gov

Registry information

Official study title

Traditional and Non-Traditional Cardiovascular Risk Factors Associated With the Lipid Profile of Hospitalized Mexican Adults: A Cross-Sectional Study With Multivariate Analysis and Structural Modeling

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 18, 2026
Registry last updated
Sep 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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