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OpenTrials
Completed

NCT Number: NCT07828600

Effects of Application of Oral Moisturizers on Microbiota Homeostasis in Long-Term Care Patients

The primary objective is to explore the differences in oral flora among healthy elderly individuals, those in a sub-healthy state, and those requiring long-term care. Furthermore, it will investigate whether different mental states, lifestyles, or dietary habits lead to variations in dominant oral flora. The study will also observe the degree of change in oral flora after intervention in oral hygiene care.

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Key information

Conditions

Long-Term Care Brain Diseases Central Nervous System Diseases Dementia Mental Disorders Nervous System Diseases Neurocognitive Disorders

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Meiho university

Pingtung City, Taiwan, 912

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • aged ≥65 years and having resided in the facility for ≥6 months.

Exclusion criteria

  • Individuals who were receiving systemic antimicrobial therapy were strictly excluded.

Treatment and study plan

oral moisturizer

Behavioral

A thin, uniform layer of oral moisturizing gel (GC, Japan) was topically applied directly to the dorsal surface of the tongue and the surrounding oral mucosal surface.

Primary outcomes

  1. the gingival index

    Time frame: six weeks

    mild, moderate and severe

  2. calculus and tongue plaque index

    Time frame: six weeks

    none, mild, moderate and severe

  3. Residual root

    Time frame: six weeks

    none, 0-4, more than 4

  4. dental caries

    Time frame: six weeks

    decay, missing

Sponsors and collaborators

Lead sponsor

Meiho University

Other

Registry information

Acronym: Oral Moisturiz

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 18, 2026
Registry last updated
Sep 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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