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NCT Number: NCT07823621

Neural Mechanisms of Social Feedback Evaluation in Young Adults Across the Schizotypy Spectrum: An EEG Social Judgment Study

This study will examine how young adults with different levels of schizotypal traits process social acceptance and rejection. Participants between 18 and 35 years old will complete a single laboratory session that includes questionnaires and electroencephalography (EEG), a noninvasive method that measures electrical brain activity through sensors placed on the scalp. During EEG recording, participants will complete a computer-based Social Judgment Paradigm (SJP) in which they form expectations about whether another person will like or dislike them and then receive experimentally controlled acceptance or rejection feedback. The study will examine how brain responses differ when social feedback is expected versus unexpected and whether these responses vary with schizotypal traits. The goal is to better understand the brain mechanisms involved in evaluating social feedback. This study does not provide treatment and does not test a drug or medical device.

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Key information

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Central Connecticut State University

New Britain, Connecticut, 06050, United States

About this study

Schizotypal traits occur along a continuum in the general population and are associated with differences in social functioning and social information processing. This study will investigate neural responses to social feedback in young adults across the schizotypy spectrum using electroencephalography (EEG).

Participants between 18 and 35 years old will complete a single experimental session. During EEG recording, they will perform a Social Judgment Paradigm (SJP) in which they first form an expectation about whether another person will respond positively or negatively toward them and subsequently receive acceptance or rejection feedback. This produces four within-participant feedback conditions: expected acceptance, expected rejection, unexpected acceptance, and unexpected rejection.

The study will examine brain activity associated with evaluating social feedback, including frontal-midline (FM) theta activity and event-related potentials (ERPs). The primary analyses will test whether neural responses to acceptance and rejection, particularly when feedback violates expectations, vary as a function of continuous schizotypal traits. Participants will also complete self-report measures assessing schizotypal traits, social functioning, and related psychological characteristics.

The study is designed to clarify neural mechanisms involved in social feedback evaluation and to determine how individual differences in schizotypal traits are associated with these processes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Ages 18-35 years.
  • Able to provide informed consent.
  • Able to complete an EEG recording session.

Exclusion criteria

  • Younger than 18 years or older than 35 years.
  • Unable to provide informed consent.
  • Unable to complete the EEG recording session.
  • No additional exclusion criteria are applied.

Treatment and study plan

Social Judgment Paradigm

Behavioral

A computerized Social Judgment Paradigm in which participants receive experimentally controlled social feedback (acceptance/rejection) from purported peers or evaluators while continuous EEG is recorded to assess oscillatory activity and event-related potentials associated with social feedback processing. Feedback valence and expectancy are manipulated at the trial level, with trial order randomized within the task.

Other names: SJP

Primary outcomes

  1. Frontal Midline Theta Power (4-7 Hz)

    Time frame: Day 1

    Mean frontal-midline theta-band power (4-7 Hz) derived from EEG data time-locked to feedback onset during the Social Judgment Paradigm, quantified during the prespecified 200-600 ms post-feedback window at frontocentral electrodes. Theta power will be measured directly across the four feedback conditions defined by expectancy (expected/unexpected) and feedback valence (acceptance/rejection).

  2. Feedback-Related Negativity (FRN) Amplitude

    Time frame: Day 1

    Mean event-related potential (ERP) amplitude within the 250-350 ms time window following feedback onset during the Social Judgment Paradigm, quantified at frontocentral electrodes. FRN amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.

  3. Late Positive Potential (LPP) Amplitude

    Time frame: Day 1

    Mean event-related potential (ERP) amplitude within the 350-600 ms time window following feedback onset during the Social Judgment Paradigm, quantified at midline electrodes. LPP amplitude will be measured directly across the four feedback conditions defined by expectancy and feedback valence.

Secondary outcomes

  1. Behavioral Expectancy Responses

    Time frame: Day 1

    Participant predictions of social acceptance or rejection during each trial of the Social Judgment Paradigm, including expectancy response and reaction time.

  2. Schizotypal Personality Questionnaire (SPQ) Total Score

    Time frame: Day 1

    The Schizotypal Personality Questionnaire (SPQ) is a 74-item self-report measure assessing schizotypal personality traits across cognitive-perceptual, interpersonal, and disorganized dimensions. Items are answered in a yes/no format and scored dichotomously. Item scores are summed to produce a total score ranging from 0 to 74. Higher scores indicate greater levels of schizotypal personality traits.

  3. Multidimensional Schizotypy Scale (MSS) Scores

    Time frame: Day 1

    The Multidimensional Schizotypy Scale (MSS) is a 77-item self-report measure assessing positive, negative, and disorganized dimensions of schizotypy. Items are answered using a true/false response format. The Positive Schizotypy subscale contains 26 items and ranges from 0 to 26; the Negative Schizotypy subscale contains 26 items and ranges from 0 to 26; and the Disorganized Schizotypy subscale contains 25 items and ranges from 0 to 25. Higher scores on each subscale indicate greater levels of the corresponding dimension of schizotypy.

  4. Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) Total Score

    Time frame: Day 1

    The Brief Fear of Negative Evaluation Scale-Revised (BFNES-R) is a 12-item self-report measure assessing fear of negative evaluation by others. Each item is rated on a 5-point Likert scale ranging from 0 (not at all characteristic of me) to 4 (extremely characteristic of me). Item ratings are summed to produce a total score ranging from 0 to 48. Higher scores indicate greater fear of negative evaluation and greater concern about others' social evaluation.

  5. Perceived Stress Reactivity Scale (PSRS) Total Score

    Time frame: Day 1

    The Perceived Stress Reactivity Scale (PSRS) is a 23-item self-report measure assessing an individual's typical response intensity to potentially stressful situations in everyday life. The scale includes five domains: prolonged reactivity, reactivity to failure, reactivity to social conflict, reactivity to work overload, and reactivity to social evaluation. Items are scored from 0 to 2, with negatively keyed items reverse-scored, and summed to produce a total score ranging from 0 to 46. Higher scores indicate greater perceived stress reactivity

  6. Social Functioning Questionnaire (SFQ) Total Score

    Time frame: Day 1

    The Social Functioning Questionnaire (SFQ) is an 8-item self-report measure assessing perceived social functioning across domains including work and home activities, finances, close relationships, family relationships, social isolation, sexual functioning, and leisure activities. Each item is scored from 0 to 3, and item scores are summed to produce a total score ranging from 0 to 24. Higher scores indicate poorer social functioning.

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Sponsors and collaborators

Lead sponsor

Central Connecticut State University

Other

Registry information

Official study title

Neural Mechanisms of Social Feedback Evaluation in Schizotypy: An EEG Study of Oscillatory and Event-Related Potentials

Important dates

Study start
2027
Primary completion
2029
Study completion
2029
First posted
Sep 16, 2026
Registry last updated
Sep 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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