Necessity of TSH Suppression Therapy in Active Surveillance for Thyroid Cancer Patients.
NCT06971965
Adenocarcinoma, Adenocarcinoma, Papillary
View Trial DetailsNCT Number: NCT07823439
The aim of this study is to evaluate the clinicopathological pattern and surgical outcome of papillary thyroid carcinoma (PTC) at Sohag University Hospitals. This will help improve local risk stratification, optimize surgical decision-making, and guide future management strategies for patients with PTC in this region.
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Observational
Papillary thyroid carcinoma (PTC) is the most common histological subtype of thyroid cancer, representing about 80-85% of cases. This study is a case-series study with both retrospective (June 2023 - June 2026) and prospective (June 2026 - March 2027) components, conducted at the Department of General Surgery, Sohag University Hospitals.
All patients diagnosed with papillary thyroid carcinoma and managed at Sohag University Hospitals during the study period will be included. Data collection includes baseline demographic and clinical features, preoperative laboratory tests (thyroid function tests and serum calcium), neck ultrasonography findings (ACR TI-RADS category, nodule size, and lymph node assessment), fine-needle aspiration cytology (Bethesda System), surgical intervention types (hemithyroidectomy, total thyroidectomy, and neck dissection), final histopathological characteristics (tumor size, multifocality, lymphovascular invasion, extrathyroidal extension, and nodal status), and early postoperative complications (hypocalcemia, recurrent laryngeal nerve palsy, hematoma, seroma, and wound sepsis).
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 9 months
Percentage of participants with histologically confirmed extrathyroidal extension.
Time frame: 9 months
Percentage of participants experiencing early postoperative complications including hypocalcemia, recurrent laryngeal nerve palsy, hematoma, seroma, or wound sepsis.
Time frame: 9 months
Percentage of participants found to have multifocal tumors on final histopathological examination.
Time frame: 9 months
Percentage of participants with histopathologically confirmed cervical lymph node metastasis.
Contact information is provided by the study sponsor or research team.
Ahmed Aboulabed Resident Ahmed Aboulabed Ahmed Mousa, resident
CONTACT
Sohag University
Other
Pattern and Surgical Outcome of Papillary Thyroid Cancer: A Case Series Study at Sohag University Hospitals
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