Outcomes of Traumatic Intracranial Hemorrhage in the Elderly

This observational study aims to describe the clinical and radiological characteristics of older adults (aged 65 years and older) who experience traumatic bleeding in the brain, also known as traumatic intracranial hemorrhage. In older patients, even minor head injuries like a simple ground-level fall can lead to significant brain bleeding due to age-related changes, frailty, and the frequent use of blood-thinning medications.

The researchers will prospectively monitor geriatric patients admitted to the hospital with a traumatic brain bleed confirmed by a CT scan who are being treated conservatively (without surgery). During the hospital stay, the research team will collect data on the patients' pre-injury health status, current clinical condition, and specific findings on their brain scans.

The main goal of the study is to assess the patients' functional recovery and survival by the time they are discharged from the hospital. By observing these cases, the study seeks to identify which specific clinical signs and radiological factors help predict poor or favorable outcomes, ultimately aiming to improve the management and care of older adults with head trauma.

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Key information

Conditions

Traumatic Brain Injury Brain Diseases Brain Injuries Brain Injuries, Traumatic Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Craniocerebral Trauma Epidural Hematoma Hematoma Hematoma, Epidural, Spinal Hematoma, Subdural Hemorrhage Intracranial Hemorrhage, Traumatic Intracranial Hemorrhages Nervous System Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Subdural Hematoma Trauma, Nervous System Vascular Diseases Wounds and Injuries

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 65 years or older.
History of blunt or traumatic head injury.
CT-confirmed intracranial hemorrhage.
Conservatively managed patients.
Availability of clinical and radiological data.
Consecutive eligible patients during the defined study period.

Exclusion criteria

Non-traumatic intracranial hemorrhage.
Age less than 65 years.
Incomplete medical records.
Patients with major pre-existing intracranial pathology that prevents proper analysis.
Penetrating brain injury.
Surgically managed patients.

Treatment and study plan

Primary outcomes

Functional outcome assessed by the Glasgow Outcome Scale-Extended (GOSE)

Time frame: Baseline

Functional outcome will be evaluated using the Glasgow Outcome Scale-Extended (GOSE). The GOSE scale ranges from 1 to 8, where higher scores indicate a better functional outcome. The results are subsequently categorized to define an unfavorable outcome as a GOSE score of 1-4, and a favorable outcome as a GOSE score of 5-8.

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Traumatic Intracranial Hemorrhage in the Elderly: Prognostic Factors and Outcomes

Important dates

Study start: 2026
Primary completion: 2027
Study completion: 2027
First posted: Sep 16, 2026
Registry last updated: Sep 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed