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NCT Number: NCT07819630

Electroencephalogram Changes Induced by Transcutaneous Electrical Acupoint Stimulation

A total of 90 subjects underwent abdominal surgery under general anesthesia at Chaoyang Hospital in Beijing. The subjects were divided into a percutaneous acupoint electrical stimulation group and a control group. The subjects were selected for TEAS stimulation at the Neiguan, Hegu, and Zusanli acupoints on both sides, and EEG data were collected using a 32 lead EEG cap test throughout the entire process. During the experiment, changes in hemodynamic parameters (blood pressure, heart rate) and perioperative pain scores of the subjects will be recorded.

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Key information

Conditions

Postoperative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Affiliated Beijing Chaoyang Hospital of Capital Medical University, Beijing 100020

Beijing, China

Location status: Recruiting

Location contact

Wei

CONTACT

[email protected]

 +86 13810678936

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

1. Age between 18 and 80 years; 2. ASA physical status classification I-II; 3. Scheduled to undergo abdominal surgery under general anesthesia (e.g., gastrectomy, colorectal cancer surgery, etc.); 4. Consent to participate in the study and signing of the informed consent form.

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Exclusion criteria

1. Impaired cognitive function or language communication disorders; 2. Mental disorders, epilepsy, or abnormal EEG activity; 3. Receipt of acupoint therapy within two weeks prior to surgery; 4. Presence of a cardiac pacemaker or metal implants; 5. Allergy to surface electrodes; 6. Concomitant medical conditions (e.g., dermatological disorders) that may affect treatment or trial administration.

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Treatment and study plan

Transcutaneous electrical acupoint stimulation

Device

Group description: Participants in this group will receive TEAS stimulation at the bilateral Neiguan, Hegu, and Zusanli acupoints 30 minutes before the start of the surgery, and their EEG data will be collected throughout the entire process using a 32 lead EEG cap test. During the experiment, the changes in hemodynamic parameters (blood pressure, heart rate) of the subjects during surgery will be recorded, as well as the perioperative pain scores of the subjects at 1 hour and 24 hours after surgery.

Primary outcomes

  1. Electroencephalogram analysis

    Time frame: Five - minute baseline EEG data with eyes closed during wakefulness；EEG data during pre - operative transcutaneous electrical acupoint stimulation；Immediate post - operative EEG data

    Changes in EEG in the experimental group with transcutaneous electrical acupoint stimulation compared to the baseline, as well as post - operative EEG changes in the experimental group and the control group.Including：node clustering coefficient，node efficiency，normalized mean clustering coefficient，normalized path length，modularity，small-world network

Secondary outcomes

  1. Patients' VAS score

    Time frame: 24 hours after surgery

    Patients' VAS scores24 hours after surgery

Study contacts

Contact information is provided by the study sponsor or research team.

Wei

CONTACT

[email protected]

 +86 13810678936

Sponsors and collaborators

Lead sponsor

Beijing Chao Yang Hospital

Other

Registry information

Official study title

Randomized Controlled Trial on the Effects of Transcutaneous Electroacupuncture on Brain Functional Connectivity in Postoperative Pain Patients Based on Electroencephalography

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Sep 15, 2026
Registry last updated
Sep 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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