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Completed

NCT Number: NCT07810387

Sex Differences in Knee Strength and Speed in Male and Female Football Players

Force-velocity (F-V) profiling is increasingly used to describe the mechanical capacities of the knee extensors and knee flexors in football, but almost all available reference data come from male players. It is not established whether male and female players differ in the parameters of the isokinetic force-velocity relationship, or whether any such differences persist once differences in body size are accounted for.

This single-centre, cross-sectional observational study compared the isokinetic force-velocity profiles of the knee extensors and knee flexors between male and female competitive football players. Eligible participants were competitive players aged 18 to 35 years, training at least three times per week, free of current lower limb pain or injury and with no history of knee or hip surgery. During a single testing session, participants performed bilateral concentric isokinetic knee extension and flexion at five angular velocities (30, 60, 180, 240 and 300 degrees per second) on an isokinetic dynamometer, after a standardised warm-up, individual gravity correction and a familiarisation session.

For each participant, limb and muscle group, peak torque was regressed against angular velocity to fit an individual linear torque-angular velocity relationship. The following parameters were derived: theoretical maximal torque (F0), theoretical maximal angular velocity (V0), the slope of the relationship, maximal theoretical power (Pmax), and torque and power at the extremes of the tested velocity range. The participant, defined as the mean of both limbs, was the unit of analysis.

Male and female players were compared in absolute terms and after adjustment for body size, using ratio scaling to body mass, log-log allometric models and analysis of covariance with body mass and age as covariates. Secondary comparisons included the conventional hamstring-to-quadriceps ratio, inter-limb asymmetry and the orientation of the profile (F0/V0 ratio).

The purpose of the study is to determine which sex differences in isokinetic force-velocity parameters are explained by body size and which persist after adjustment, in order to establish whether reference values obtained in male players can legitimately be applied to female players.

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Key information

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Orthosport Center

Domont, 95330, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male or female football players aged 18-35 years;
  • participation in competitive football for at least three consecutive years;
  • a minimum of three weekly training sessions;
  • no current pain or injury of the lower limbs;
  • no history of knee or hip surgery;
  • ability to perform maximal voluntary contractions during isokinetic testing;
  • an adequate physical activity level (Tegner ≥ 7; Marx ≥ 12).

Exclusion criteria

  • any medical condition limiting the test or any injury/surgery of the lower limb from the last 2 years

Treatment and study plan

Isokinetic test

Diagnostic Test

The expected results should improve the objective characterisation of residual deficits, inform the selection and prioritisation of the tests used in return-to-sport assessments, and contribute to evidence-based rehabilitation practice. The project thereby contributes to improving quality of care and to generating knowledge that is useful to the health professionals managing this population. No procedure is added to routine care, and the care pathway is not modified.

Primary outcomes

  1. Isokinetic force-velocity profile of the knee extensors and knee flexors

    Time frame: Day 1(single isokinetic testing session)

    Force-velocity profile of the knee extensors and knee flexors derived from isokinetic dynamometry, compared between male and female competitive football players. [ e.g. theoretical maximal force F0, theoretical maximal velocity V0, and the slope of the force-velocity relationship, with units.]

Sponsors and collaborators

Lead sponsor

Haute Ecole ARC Sante

Other

Registry information

Official study title

Sex-Based Differences in Isokinetic Force-Velocity Profiles of the Knee Extensors and Flexors in Male and Female Football Players: A Cross-Sectional Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 9, 2026
Registry last updated
Sep 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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