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OpenTrials
Active, not recruiting

NCT Number: NCT07808047

Dynamic Pupil Variations and the Efficacy of Peripheral Defocus Spectacle Lenses in Slowing Myopia Progression

to evaluate the correlation between dynamic pupil variations and the efficacy of spectacle lenses in myopia progression control

Active, not recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Myopia Progressing Eye Diseases Myopia Refractive Errors

Age range

6 year–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Luca Buzzonetti

Roma, Italy

About this study

to evaluate if the dynamic nature of the pupil throughout the day could directly modulates the efficacy of spectacle lenses in myopia progression control in European pediatric patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

progressive myopia

Exclusion criteria

suspected genetic syndromes all systemic or eye diseases

Treatment and study plan

perifheral defocus spectacle lenses

Device

dynamic pupillometry measurement

peripheral defocus spectacle lens

Device

24 month follow up

Primary outcomes

  1. pupil diameter change

    Time frame: From enrollment to 24 months follow up

  2. correlation between dynamic pupil and axial lenght change

    Time frame: from enrollment to 24 monts

Sponsors and collaborators

Lead sponsor

Bambino Gesù Hospital and Research Institute

Other

Registry information

Official study title

Correlation Between Dynamic Pupil Variations and the Efficacy of Peripheral Defocus Spectacle Lenses in Slowing Myopia Progression in Pediatric Patients

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Sep 8, 2026
Registry last updated
Sep 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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