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NCT Number: NCT07806968

Effect of Postural Correction Exercises on Pelvic Floor Dysfunction in Postmenopausal Osteoporotic Women

This study aimed to investigate the effect of postural correction exercises on pelvic floor dysfunction in postmenopausal osteoporotic women

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Key information

Age range

55 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Osteoporosis is a progressive musculoskeletal disease that significantly affects postmenopausal women, leading not only to reduced bone density but also to altered spinal and pelvic alignment, which negatively impacts functional capacity and quality of life. These postural deviations are associated with changes in pelvic biomechanics and increased prevalence of pelvic floor muscle (PFM) dysfunction.

Pelvic floor dysfunction in postmenopausal women is a major health concern, manifesting as urinary incontinence, pelvic discomfort, and reduced core stability. Recent evidence suggests a strong relationship between pelvic tilt, lumbar lordosis, and pelvic floor muscle function, indicating that abnormal posture may compromise pelvic floor support and contribute to dysfunction and symptomatic severity. This highlights the biomechanical interdependence between posture and pelvic floor activity.

Emerging evidence suggests a potential association between osteoporosis and pelvic floor dysfunction (PFD). Studies have demonstrated that reduced bone strength and low bone mineral density are associated with a higher prevalence of pelvic floor symptoms among postmenopausal women.

Pelvic floor muscle training (PFMT) is widely recognized as a first-line conservative treatment for pelvic floor dysfunction (PFD) However, emerging evidence suggests that PFMT alone may not be sufficient to fully address symptoms in all individuals, especially when underlying biomechanical and postural factors are present. Recent studies have highlighted the importance of lumbopelvic alignment and postural control in optimizing pelvic floor muscle function, as alterations in spinal curvature and pelvic tilt can influence muscle activation and intra-abdominal pressure distribution.

Interventions that target postural correction may therefore play a crucial role in optimizing pelvic floor function. A clinical study demonstrated that posture correction therapy, including postural alignment and behavioral modifications, significantly influenced pelvic floor muscle activity as measured by electromyography in women suggesting that addressing postural deviations may enhance pelvic floor rehabilitation outcomes.

Furthermore, postural and stabilization exercises focusing on spinal alignment have been shown to improve pelvic floor muscle strength, core stability, urinary symptoms, and quality of life in women with functional pelvic disorders such as overactive bladder.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Postmenopausal women with ages between 55 and 65 years.
  • Their body mass index will not exceed 35 Kg/m2.
  • All women have mild to moderate pelvic floor muscle dysfunction.
  • All women were diagnosed with osteoporosis confirmed by Dual-energy X-ray Absorptiometry (DEXA) (T-score ≤ -2.5).

Exclusion criteria

  • Women will be excluded if they have one or more of the following:
  • Previous pelvic or abdominal surgery affecting pelvic floor function.
  • Severe pelvic organ prolapse (Grade III or IV).
  • Neurological disorders affecting pelvic floor or lower limb function.
  • Severe musculoskeletal disorders limiting exercise participation.
  • Current participation in pelvic floor rehabilitation programs during the last 6 months.
  • Severe cardiovascular or respiratory conditions contraindicating exercise.

Treatment and study plan

estrogen replacement therapy

Drug

The participants will receive estrogen replacement therapy for 3 months to enhance postmenopausal symptoms and their quality of life

General advice

Other

Postmenopausal women will be instructed to maintain a neutral spinal alignment during sitting, standing, and daily activities, avoid prolonged slouched sitting, and use supportive seating to encourage correct posture. Light to moderate physical activity, such as daily walking, will be encouraged to reduce sedentary behavior and maintain overall physical function. women will also receive guidance on healthy bowel and bladder habits, including avoiding straining during bowel movements and unnecessary frequent urination, as increased intra-abdominal pressure can worsen pelvic floor dysfunction.

Postural correction exercise program

Other

The participants will follow a structured postural correction exercise program, 3 times per week for 12 weeks, each session lasting 45-60 minutes.

Primary outcomes

  1. Pelvic Floor Muscle Assessment

    Time frame: 12 weeks

    Pelvic floor muscle function will be assessed using surface electromyographic (EMG) to measure muscle activation patterns. For the measurement, women will be placed in a supine position with knees flexed. A vaginal surface probe electrode will be gently inserted to record pelvic floor muscle (PFM) activity, and a reference electrode will be placed on a bony landmark such as the anterior superior iliac spine to reduce electrical noise. Participants will be instructed to contract their pelvic floor muscles as if stopping urine flow, holding each contraction for 5 seconds, followed by 10 seconds of relaxation. Each contraction will be repeated three times, and the highest root mean square RMS amplitude of the three contractions will be used for analysis. EMG signals will be processed to calculate RMS amplitude and normalized to maximum voluntary contraction for inter-individual comparisons

  2. Kyphotic angle

    Time frame: 12 weeks

    Formetric System will be used to evaluate spinal alignment parameters including thoracic kyphosis before and after treatment The system is a non-invasive, radiation-free optical imaging technology that projects a light grid onto the back surface and captures the reflected pattern using a high-resolution digital camera. Using surface topography, the software reconstructs a three-dimensional model of the back allowing precise calculation of spinal angles. Thoracic kyphosis angle is measured as the angle between tangent lines at the upper and lower thoracic vertebrae.

  3. Lumbar lordotic angle

    Time frame: 12 weeks

    Formetric System will be used to evaluate spinal alignment parameters including lumbar lordosis before and after treatment The system is a non-invasive, radiation-free optical imaging technology that projects a light grid onto the back surface and captures the reflected pattern using a high-resolution digital camera. Using surface topography, the software reconstructs a three-dimensional model of the back allowing precise calculation of spinal angles. Lumbar lordosis angle as the angle between tangent lines at the upper lumbar and sacral vertebrae.

Secondary outcomes

  1. Menopause-specific quality of life questionnaire

    Time frame: 12 Weeks

    The MENQOL is self-administered and consists of a total of 29 items in a Likert-scale format. Each item assesses the impact of one of four domains of menopausal symptoms, as experienced over the last month: vasomotor (items 1-3), psychosocial (items 4-10), physical (items 11-26), and sexual (items 27-29). Items pertaining to a specific symptom are rated as present or not present, and if present, how bothersome on a zero (not bothersome) to six (extremely bothersome) scale

Study contacts

Contact information is provided by the study sponsor or research team.

Alaa M Ebrahim, Master

CONTACT

[email protected]

01090988989

Mahitab M Yosri, PHD

CONTACT

[email protected]

01222606996

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Sep 8, 2026
Registry last updated
Sep 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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