Prospective Feasibility, Analgesic Effectiveness, and Safety Study of a Visual Analog Scale-Guided Multimodal Pain Algorithm After Posterior Rib Remodeling With Osteosynthesis

After RIBOSS surgery, participants will enter a structured analgesia pathway based on repeated 0-to-10 pain scores. Mild pain will receive a nonopioid base regimen; moderate pain will prompt addition of an NMDA-directed and elastomeric multimodal strategy with optional regional block; severe pain will prompt full multimodal infusion and regional rescue when safe. Assessments will occur at 6, 12, and 24 hours and every 12 hours through day 5. Each assessment will document pain at rest and movement, active treatment tier, rescue interventions, sedation, respiratory status, nausea/vomiting, and other adverse events. The study will determine whether the algorithm consistently achieves adequate analgesia and can be implemented safely and reproducibly.

Inclusion criteria

• Age 18 to 55 years.
• Scheduled for posterior aesthetic rib remodeling with osteosynthesis using the standardized RIBOSS technique.
• Ability to understand and use a 0-to-10 visual analog or numeric pain scale.
• Availability for scheduled pain assessments through postoperative hour 120.
• Written informed consent.

Exclusion criteria

• Chronic opioid use or opioid use disorder requiring an individualized perioperative plan.
• Contraindication to the base nonsteroidal anti-inflammatory drug or acetaminophen regimen and inability to use the predefined alternative pathway.
• Contraindication to ketamine, lidocaine, dexmedetomidine, or the planned regional block when those components may be required.
• Severe hepatic, renal, cardiac, neurologic, or psychiatric condition judged to make the algorithm unsafe.
• Pregnancy or breastfeeding.
• Inability to provide reliable pain scores or complete five-day monitoring.