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NCT Number: NCT07802054

Messages That Motivate: Communicating Alcohol-Related Breast Cancer Risk to Young Adult Women

This is an online cross-sectional experimental survey study examining two cancer communication questions: 1) What features of social media messages communicating the breast cancer risks from alcohol consumption will motivate young adult women to drink less? and 2) Do message features differ in their persuasive effects based on young adult women's alcohol consumption behavior?

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Key information

Age range

18 year–25 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

The Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States

Location contact

Darren Mays, MPH, PhD

CONTACT

[email protected]

614-366-2953

Darren Mays, MPH, PhD

PRINCIPAL_INVESTIGATOR

About this study

This is an online cross-sectional experimental study to examine the effects of features of social media messages in young adult women ages 18-25 who drink alcohol based on valid, self-report outcomes. Within the survey, participants will be randomized to view messages in one of nine conditions in a 3x3 factorial design with baseline alcohol consumption as a within-participants factor to test the effects of social media message features (content, persuasive themes) on participant responses. We will also compare the effects of message features for young women who drink within recommended limits (1 drink/day or less on average) and those who exceed recommended drinking limits.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Assigned female at birth
  • Age 18-25
  • Report drinking alcohol at least once in the past 30 days
  • Registered in the United States as a member of the Prolific consumer research platform
  • Willing and able to complete procedures in English

Exclusion criteria

  • Assigned male at birth
  • Ages <18 or >25
  • Do not report drinking alcohol at least once in the past 30 days
  • Not registered in the U.S. as a member of the Prolific consumer research platform
  • Not willing or not able to complete procedures

Treatment and study plan

Risk Message

Behavioral

Risk message content

Efficacy Message

Behavioral

Efficacy Message Content

Industry Deception

Behavioral

Messages with information about alcohol industry deception

YAW Susceptibility

Behavioral

Message content with information about why young adult women are susceptible to breast cancer risk from alcohol consumption

Mechanisms

Behavioral

Message content with information about the mechanism by which alcohol contributes to increased breast cancer risk

Primary outcomes

  1. Message Perceptions

    Time frame: This assessment is administered immediately after participants view study messages on Day 1

    We will assess message perceptions using a valid, reliable measure with six questions about whether participants thought the messages were worth remembering, grabbed their attention, and were informative, powerful, convincing, and meaningful. Responses are on a five-point Likert scale from 1 (Strongly disagree) to 5 (Strongly agree).

    For all message response outcomes, we will sum and average responses to the items to create message-level scores, then compute means across both messages within each condition for a grand mean. Higher values are considered a better outcome.

  2. Effect Perceptions

    Time frame: This assessment is administered immediately after participants view study messages on Day 1

    We will capture message effects perceptions using the abbreviated effects perceptions scale. Items include questions about how much the messages made them feel discouraged to drink alcohol, concerned about drinking alcohol, and made them feel that drinking alcohol is unpleasant on a scale from 1 (Strongly disagree) to 5 (Strongly agree). For all message response outcomes, we will sum and average responses to the items to create message-level scores, then compute means across both messages within each condition for a grand mean. Higher values are considered a better outcome.

  3. Emotional Response

    Time frame: This assessment is administered immediately after participants view study messages on Day 1

    We will capture emotional responses to the messages using a valid, four item scale. Items are "This message made me angry; irritated; aggravated; and annoyed" with responses on a 5-point Likert scale from 1 (Not likely at all) to 5 (Extremely likely). For all message response outcomes, we will sum and average responses to the items to create message-level scores, then compute means across both messages within each condition for a grand mean. Higher values are considered a better outcome.

  4. Counter-arguing

    Time frame: This assessment is administered immediately after participants view study messages on Day 1

    We will capture counter-arguing, a measure of whether participants cognitively refute messages, with a valid, three item scale that captures whether participants criticize messages, think of points that go against messages, and are skeptical of the messages. Responses are on a 5-point Likert scale ranging from 1 (Not at all) to 7 (Very much). For all message response outcomes, we will sum and average responses to the items to create message-level scores, then compute means across both messages within each condition for a grand mean. Lower values are considered a better outcome.

  5. Behavioral Intentions

    Time frame: This assessment is administered immediately after participants view study messages on Day 1

    Intentions to reduce alcohol consumption in the future will also be assessed with a valid, multi-item scale capturing whether participants will avoid drinking alcohol completely, reduce the number of occasions when they drink alcohol, and reduce the amount of alcohol they consume on drinking occasions with a 1 (Definitely Will Not) to 4 (Definitely Will) response scale. For all message response outcomes, we will sum and average responses to the items to create message-level scores, then compute means across both messages within each condition for a grand mean. Higher values are considered a better outcome.

Study contacts

Contact information is provided by the study sponsor or research team.

The Ohio State University Comprehensive Cancer Center

CONTACT

[email protected]

800-293-5066

Sponsors and collaborators

Lead sponsor

Ohio State University Comprehensive Cancer Center

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Acronym: MEMO

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Sep 3, 2026
Registry last updated
Sep 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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