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NCT Number: NCT07801482

Supplementary Neuromuscular Rehabilitation During Acute Concussion Recovery

Approximately 1.6 to 3.8 million mild traumatic brain injuries, or concussions, occur yearly in the United States. Although most individuals progress through return-to-activity (RTA) using symptom-guided aerobic and functional activity, current protocols do not directly target neuromuscular deficits linked to persistent movement alterations after concussion. These deficits include altered gait, reduced movement efficiency, and biomechanical changes that persist beyond symptom resolution and increase subsequent risk of musculoskeletal injury. This creates a critical clinical gap: patients are cleared using symptom-tolerance protocols, while concussion-related neuromuscular impairments remain untreated during the period when recovery behaviors are established. The proposed project addresses this gap by testing a low-cost, equipment-free neuromuscular rehabilitation strategy added to standard RTA during acute concussion recovery. The intervention applies the six principles of clinical Pilates, concentration, control, centering, precision, flow, and breathing, through ten therapeutic movements designed to improve posture, flexibility, balance, strength, muscle control, body awareness, and movement confidence.

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Key information

Age range

18 year–24 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

Northern Illinois University

DeKalb, Illinois, 60115, United States

Location contact

Tyler A Wood, PhD, LAT, ATC

CONTACT

[email protected]

815-753-1418

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • aged 18 to 24 years old
  • be a registered member of an intercollegiate sports team
  • have received a medically confirmed concussion within 7 days of the initial study visit.

Exclusion criteria

  • moderate or severe traumatic brain injury
  • red-flag signs or symptoms requiring urgent medical evaluation
  • current lower-extremity injury that prevents safe walking or therapeutic exercise
  • a neurological or vestibular disorder unrelated to concussion that independently affects balance or gait
  • an uncorrected visual impairment that prevents completion of testing
  • any medical condition that prevents participation in symptom-guided physical activity

Treatment and study plan

Exercise

Behavioral

The intervention will include 10 standardized exercises: pelvic tilts, bridging, seated spinal twists, bent-knee fallouts, supine toe taps, clamshells, side-lying leg lifts, supine side-to-sides, quadruped arm and leg reach, and standing roll downs. Not every exercise will be performed during every session. Exercise selection will follow a prespecified intervention framework designed to provide consistent exposure to the major movement domains of the protocol while permitting symptom-guided modification. The standardized protocol will identify the exercises eligible for each stage of progression and the criteria required to advance to more demanding movements. Research personnel will select exercises from the appropriate stage based on the participant's current tolerance, symptom response, movement quality, and prior session performance.

Other names: Supplementary Neuromuscular Rehabilitation

Return to Activity Progression

Behavioral

A research team member will attend each RTA session to collect symptom ratings immediately before and after the session. Assessments will occur whenever the athlete completes an RTA session, up to five days per week, between days 7 and 35 after concussion. These repeated observations will characterize symptom response to standard RTA throughout recovery.

Primary outcomes

  1. Symptom Burden

    Time frame: Day 7 to 35

    Symptom Burdent

  2. Tandem Gait Performance

    Time frame: Day 7 to 35

    Tandem Gait time to complete

  3. Recovery Time

    Time frame: Day 7 to 35

    Time to Recovery

Study contacts

Contact information is provided by the study sponsor or research team.

Tyler A Wood, PhD, LAT, ATC

CONTACT

[email protected]

815-753-1418

Sponsors and collaborators

Lead sponsor

Northern Illinois University

Other

Registry information

Important dates

Study start
2027
Primary completion
2030
Study completion
2030
First posted
Sep 3, 2026
Registry last updated
Sep 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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