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Enrolling by invitation

NCT Number: NCT07801339

Clinical Evaluation of Immediate Dental Implants in Very Elderly Patients.

Background: In recent years, dental implants have become a popular and effective option for replacing missing teeth, even in older adults. However, there is still limited research on implant treatments in patients aged 80 and older.

Study Details: In this study, we evaluated an 80+ year-old patient who requested dental implants after tooth extraction. The treatment involved placing an implant immediately after tooth removal, combined with bone grafting materials (Bio-Oss®) and cell-based regenerative therapy (Class III regenerative medicine). The patient continues to attend routine follow-up visits.

Goal: Because dental implants can greatly improve quality of life for elderly individuals, the goal of this study is to clinically evaluate the safety and effectiveness of implant therapy combined with regenerative medicine in patients aged 80 and older.

Enrolling by invitation

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Key information

Conditions

Tooth Loss / Rehabilitation Mouth Diseases Periodontal Diseases Stomatognathic Diseases Tooth Diseases Tooth Loss

Age range

80 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Takane Dental Clinic

Gotemba, Shizuoka, 4120018, Japan

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 80 years or older requiring dental implant therapy following tooth extraction.
  • Patients who desire dental implant treatment and provided written informed consent.
  • Patients with sufficient systemic health to undergo minor oral surgical procedures.
  • Patients willing and able to comply with scheduled follow-up visits and maintenance programs.

Exclusion criteria

  • Uncontrolled systemic diseases (e.g., uncontrolled diabetes mellitus, severe cardiovascular disease) that contraindicate oral surgery.
  • History of radiation therapy to the head and neck region.
  • Current or past use of intravenous bisphosphonates or other medications associated with osteonecrosis of the jaw.
  • Severe active periodontal disease in the remaining dentition.
  • Heavy smokers or individuals with severe parafunctional habits (e.g., severe bruxism) that may jeopardize implant integration.
  • Patients unable to attend regular follow-up appointments.

Treatment and study plan

Primary outcomes

  1. Implant Survival Rate

    Time frame: 2 year post-implantation

    Percentage of implants that remain functional, stable, and pain-free without major complications.

Sponsors and collaborators

Lead sponsor

Takane Dental Clinic

Other

Registry information

Official study title

Clinical Evaluation of Immediate Implant Placement Following Tooth Extraction in Elderly Patients Around the Age of 80.

Important dates

Study start
2025
Primary completion
2027
Study completion
2030
First posted
Sep 3, 2026
Registry last updated
Sep 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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