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NCT Number: NCT07795320

Cerebroplacental Ratio (CPR) and Amniotic-Umbilical-to-Cerebral Ratio (AUCR), in in Women With Hypertensive Disorders of Pregnancy.

The primary aim of this study is to evaluate the predictive value of the Amniotic-Umbilical-to-Cerebral Ratio (AUCR) in predicting composite adverse perinatal outcomes in women with hypertensive disorders of pregnancy and to compare its predictive performance with the traditional Cerebroplacental Ratio (CPR)

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Key information

Conditions

Hypertension Disorders in Pregnancy

Age range

18 year–40 year

Sex eligibility

Female

Study type

Observational

About this study

A prospective cohort study will be conducted to compare the predictive accuracy of the cerebroplacental ratio (CPR) and the amniotic-umbilical-to-cerebral ratio (AUCR) for composite adverse perinatal outcomes among women with hypertensive disorders of pregnancy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women aged 18-40 years, inclusive.
  • Singleton viable pregnancy.
  • Gestational age ≥32 weeks.
  • Pregnancy complicated by a hypertensive disorder.
  • Women who provide written informed consent.

Exclusion criteria

  • Multiple gestation.
  • Fetuses with known chromosomal or major congenital anomalies.
  • Maternal diseases likely to independently affect fetal circulation or perinatal outcome, such as significant cardiac disease or other major systemic diseases.
  • Inability to complete the required follow-up.

Treatment and study plan

Primary outcomes

  1. number of cases with NICU admission

    Time frame: 6 weeks

    number of neonates admitted in neonatal care unit within 24 hours after delivery

Secondary outcomes

  1. weight of birth

    Time frame: 1 day

    birth weight in grams after delivery

Study contacts

Contact information is provided by the study sponsor or research team.

Abdelrahman Mahmoud, MD

CONTACT

[email protected]

08802089519

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Comparison Between Cerebroplacental Ratio (CPR) and Amniotic-Umbilical-to-Cerebral Ratio (AUCR), in Predicting of Adverse Perinatal Outcome in Women With Hypertensive Disorders of Pregnancy.

Acronym: CPR_AUCR2026

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Aug 31, 2026
Registry last updated
Aug 31, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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