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NCT Number: NCT07793123

Effect of an Antioxidant Dietary Supplement on Skin Radiance

A randomized, double-blind, placebo-controlled study evaluating the effects of an oral antioxidant dietary supplement on skin radiance in women exposed to urban air pollution. Secondary assessments include skin tone homogeneity, pigmentation, inflammation, skin barrier function, glycation markers.

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Key information

Conditions

Healthy Women

Age range

35 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy female aged 35 to 65 years
  • Fitzpatrick skin phototype II to IV
  • All skin types
  • Dull and uneven skin tone
  • Living in an urban environment and exposed to air pollution
  • Able to comply with study procedures
  • Written informed consent provided

Exclusion criteria

  • Pregnant or breastfeeding
  • Current use of dietary supplements or vitamin supplements
  • Specific dietary restrictions
  • Unstable medication affecting water retention
  • Active medical disease
  • Facial dermatological disorder
  • Participation in another clinical trial
  • Vulnerable populations according to French regulations

Treatment and study plan

Antioxidant supplement

Dietary Supplement

Oral antioxidant dietary supplement administered as one capsule once daily for 90 days.

Placebo

Dietary Supplement

Placebo dietary supplement administered as one capsule once daily for 90 days.

Primary outcomes

  1. Skin Radiance

    Time frame: Day 0 and Day 90

    Glossymeter

Secondary outcomes

  1. Skin Radiance

    Time frame: Day 0 and Day 30

    Glossymeter

  2. Skin Radiance

    Time frame: Day 0, Day 30, Day 90

    Clinical scoring

  3. Skin homogeneity

    Time frame: Day 0, Day 30, Day 90

    VISIA CR5

  4. Skin homogeneity

    Time frame: Day 0, Day 30, Day 90

    Chromameter

  5. TransEpidermal Water Loss

    Time frame: Day 0, Day 30, Day 90

    Tewameter

  6. Skin glycation

    Time frame: Day 0, Day 30, Day 90

    AGEscanner

  7. skin IL8

    Time frame: Day 0, Day 30, Day 90

    IL8 assay

Study contacts

Contact information is provided by the study sponsor or research team.

Audrey Gauthier

CONTACT

[email protected]

+33 484 85 96 82

Pascale Berthon

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Robertet SA

Industry

Registry information

Official study title

Randomized Double-Blind Placebo-Controlled Trial Evaluating the Effect of an Oral Antioxidant Dietary Supplement on Skin Radiance in Women Exposed to Urban Air Pollution

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 28, 2026
Registry last updated
Aug 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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