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NCT Number: NCT07791108

Outcomes of Intra-articular Steroid Injection Via Ultrasound Guidance Versus Fluoroscopic Guidance in the Sacroiliac Joint in Patients With Sacroiliitis

Sacroiliitis is a common cause of low back and buttock pain. Intra-articular steroid injection of the sacroiliac joint can provide pain relief and functional improvement. This randomized controlled trial aims to compare the outcomes of ultrasound-guided versus fluoroscopic-guided sacroiliac joint steroid injections in patients with sacroiliitis. The study will evaluate procedural success, pain reduction, and functional improvement using the Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) at follow-up intervals.

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Key information

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Allied Hospital Faisalabad

Faisalābad, Punjab Province, 38000, Pakistan

About this study

The sacroiliac joint (SIJ) is increasingly recognized as a contributor to low back pain (LBP), with epidemiological estimates attributing approximately 10-30 % of mechanical low back pain cases to SIJ pathology1. Anatomically, the SIJ is a synovial-type (inferior portion) or syndesmosis-type (superior portion) joint between the sacrum and the ilium, supported by substantial interosseous, posterior and anterior ligaments and innervated by dorsal sacral rami and lower lumbar dorsal rami2. Inflammatory involvement of the SIJ occurs in conditions such as axial spondyloarthritis and may also arise post-traumatically or degeneratively3.

NSAIDs and physical therapies are used to treat sacroiliitis. However, intraarticular corticosteroid injections administered locally to the SI joint might result in rapid and significant clinical improvements in extremely painful instances4,5. Fluoroscope guided (FL) is usually employed to increase the precision of this treatment, however CT and MRI have also been used in recent years. These imaging techniques have a number of drawbacks, such as radiation exposure, expense, and the need for suitable infrastructure6. A new alternative technique for guiding SIJ injection is ultrasound (US) guidance. The advantages of US-guided injection over FL include that it eliminates radiation exposure, is more accessible, and is less expensive when used alone. Additionally, the US permits "real-time" visualisation of the injectate distribution and needle tip during injection.7,8.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-70 years
  • Both sexes
  • Clinical diagnosis of sacroiliitis

Exclusion criteria

  • Prior SI joint injection in the past 12 months
  • Contraindication to corticosteroid injection (systemic infection, local infection, bleeding diathesis, uncontrolled diabetes with HbA1c >9%, allergy to contrast or steroid)
  • Radicular or neurogenic pain attributable to lumbar spine or hip pathology
  • Pregnancy or breastfeeding
  • Severe osteoarthritis or fusion of the SI joint on imaging
  • Systemic rheumatologic disease requiring systemic biologic therapy (unless stable for >6 months)

Treatment and study plan

Ultrasound-guided intra-articular steroid injection

Procedure

Participants will receive intra-articular sacroiliac joint steroid injection under ultrasound guidance. A needle will be advanced under real-time ultrasound guidance to the sacroiliac joint, and 40 mg triamcinolone acetonide mixed with 1 mL 0.25% bupivacaine will be injected.

Other names: Ultrasound-guided SI Joint Injection

Primary outcomes

  1. Procedural success rate of sacroiliac joint injection

    Time frame: During the procedure

    Successful intra-articular deposition of steroid in the sacroiliac joint confirmed by the respective imaging guidance modality (ultrasound or fluoroscopy).

Secondary outcomes

  1. Oswestry Disability Index (ODI) Score

    Time frame: Baseline, 2 weeks, 1 month, and 3 months after the procedure

    Successful intra-articular deposition of steroid in the sacroiliac joint confirmed by the respective imaging guidance modality (ultrasound or fluoroscopy).

Study contacts

Contact information is provided by the study sponsor or research team.

Dr.Tahir Aslam Tahir, MBBS, FCPS Orthopedics

CONTACT

[email protected]

+923004499924

Sponsors and collaborators

Lead sponsor

Allied Hospital Faisalabad

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 27, 2026
Registry last updated
Aug 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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