Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension)

This monocentre prospective trial aims to evaluate the relationship between fasting time and the occurence of PIH (post-induction hypotension).

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Key information

Conditions

Post-Induction Hypotension Behavior Fasting Feeding Behavior

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Ostrava

Ostrava, Moravian-Silesian Region, 70852, Czechia

Location status: Recruiting

About this study

A decrease in blood pressure (BP) after induction of general anesthesia (GA) is a common phenomenon. The etiology is multifactorial (vasodilatory and dále negative inotropic effects of anaesthetics, reduction in sympathetic tone, the effect of positive pressure ventilation and others). Relative hypovolemia due to patient fasting is one of the factors that can have a significant influence on the decrease in blood pressure after induction of GA. Different lengths of fasting may thus lead to variations in both the incidence of hypotension after induction of GA (post-induction hypotension - PIH) and the severity of the BP drop.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age ≥ 18 years
Patients undergoing planned surgical or diagnostic procedure
Intubation under general anaesthesia

Exclusion criteria

Pregnancy
Disagreement with participation in the study
Bowel preparation

Treatment and study plan

Primary outcomes

Post induction hypotension (PIH)

Time frame: 1 month

The incidence of the post induction hypotension (PIH) will be assessed in the study subjects.
Seriousness of post induction hypotension (PIH)

Time frame: 1 month

Seriousness of post induction hypotension (PIH) will be assessed to determine whether patients with longer fasting time experience a significant reduction of blood pressure after induction of general anaesthesia.
Comparison of other PIH risk factors

Time frame: 1 month

The risk factors such as comordibity, chronic medication, type and doses of induction drugs will be compared.

Interested in participating?

Recruiting

Interested in participating?

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Sponsors and collaborators

Lead sponsor

University Hospital Ostrava

Other

Registry information

Official study title

Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension) - Prospective Trial

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Aug 25, 2026
Registry last updated: Aug 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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