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NCT Number: NCT07785570

Hamstring Versus Quadriceps Tendon Graft for MPFL Reconstruction

This prospective comparative study compared the clinical and radiological outcomes of medial patellofemoral ligament (MPFL) reconstruction using a hamstring tendon graft versus a quadriceps tendon graft in patients with recurrent patellar dislocation. The study included 38 patients with 40 affected knees who underwent MPFL reconstruction using either a hamstring tendon graft or a quadriceps tendon graft, according to the treating surgeon's preference. Patients were prospectively followed in two groups according to the graft used. Clinical outcomes were assessed using the Kujala, International Knee Documentation Committee (IKDC), and Tegner-Lysholm scores. Radiological assessment included patellar tilt angle and congruence angle. Postoperative complications and recurrent patellar instability were also evaluated.

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Key information

Conditions

Recurrent Patellar Dislocation Joint Diseases Joint Dislocations Knee Injuries Leg Injuries Musculoskeletal Diseases Patellar Dislocation Wounds and Injuries

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Cairo University Hospitals (Kasr Al-Ainy)

Cairo, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with recurrent patellar dislocation.
  • Age from 18 to 40 years.
  • Patients indicated for isolated medial patellofemoral ligament (MPFL) reconstruction.

Exclusion criteria

  • Patients with trochlear dysplasia (Dejour B-C-D).
  • Patients with clinical evidence of mal-alignment (varus, valgus, flat foot and femoral anteversion).
  • Patients with congenital pateller dislocation.
  • Patella alta and patella baja.
  • Previous quadriceps muscles operation.
  • Patients with patellofemoral OA.
  • Patients with hypermobility syndrome.
  • Patients with associated pathology.

Treatment and study plan

MPFL Reconstruction Using Hamstring Tendon Graft

Procedure

Medial patellofemoral ligament reconstruction was performed using an autologous semitendinosus tendon graft. The graft was fixed to the medial aspect of the patella and passed between layers 2 and 3 of the medial knee structures, followed by femoral fixation at the anatomical MPFL insertion.

MPFL Reconstruction Using Quadriceps Tendon Graft

Procedure

Medial patellofemoral ligament reconstruction was performed using a distally based superficial quadriceps tendon graft. The graft remained attached to the superior pole of the patella, was passed between layers 2 and 3 of the medial knee structures, and was fixed at the anatomical femoral insertion of the MPFL.

Primary outcomes

  1. Kujala score

    Time frame: 12 months postoperatively

    Functional outcome assessed using the Kujala anterior knee pain scale. The score ranges from 0 to 100, with higher scores indicating better knee function and fewer patellofemoral symptoms.

Secondary outcomes

  1. International Knee Documentation Committee (IKDC) Score

    Time frame: 12 months postoperatively

    Knee function was assessed using the International Knee Documentation Committee (IKDC) score. Scores range from 0 to 100, with higher scores indicating better knee function.

  2. Tegner-Lysholm Knee Score

    Time frame: 12 months postoperatively

    Knee function was assessed using the Tegner-Lysholm knee score. Scores range from 0 to 100, with higher scores indicating better knee function.

  3. Patellar Tilt Angle

    Time frame: 12 months postoperatively

    Patellar tilt angle was measured radiologically to assess patellofemoral alignment before and after MPFL reconstruction.

  4. Congruence Angle

    Time frame: 12 months postoperatively

    Congruence angle was measured radiologically to assess patellofemoral alignment before and after MPFL reconstruction.

  5. Incidence of Re-dislocation

    Time frame: 12 months postoperatively

    Number of cases who experienced re-dislocation after MPFL reconstruction

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Comparison Between Hamstring Versus Quadriceps Tendon Graft in MPFL Reconstruction for Recurrent Patellar Dislocation

Important dates

Study start
2018
Primary completion
2022
Study completion
2022
First posted
Aug 25, 2026
Registry last updated
Aug 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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