T.H.Q hospital
Gujar Khan, Punjab Province, Pakistan
Location status: Recruiting
Location contact
Dr.Sarmaad Kayyani, MBBS
CONTACT
Sadia Akhtar, DPT
PRINCIPAL_INVESTIGATOR
NCT Number: NCT07784998
This comparative experimental study aims to evaluate the effectiveness of Sensory-Modulated Graded Weight-Bearing Physiotherapy (SMGWBP) in patients with knee osteoarthritis and compare treatment outcomes between male and female participants. Participants will receive a 6-week physiotherapy program with assessments conducted at baseline (pre-intervention), mid-intervention (3 weeks), and post-intervention (6 weeks) using validated outcome measures.
Interested in participating?
Request Info40 year–60 year
All sexes
Interventional
Not applicable
Gujar Khan, Punjab Province, Pakistan
Location status: Recruiting
Dr.Sarmaad Kayyani, MBBS
CONTACT
Sadia Akhtar, DPT
PRINCIPAL_INVESTIGATOR
Knee osteoarthritis (KOA) is a common degenerative joint disorder associated with pain, impaired physical function, reduced proprioception, decreased mobility, and poor quality of life. Physiotherapy plays a central role in the conservative management of KOA by reducing pain and improving functional performance. Sensory-Modulated Graded Weight-Bearing Physiotherapy (SMGWBP) integrates sensory stimulation with progressive weight-bearing exercises to enhance neuromuscular control, balance, proprioception, and functional recovery.
This comparative experimental study aims to evaluate the effectiveness of SMGWBP in individuals with Kellgren-Lawrence grade II or III knee osteoarthritis and to compare treatment outcomes between male and female participants. A total of 52 participants will be recruited through purposive sampling. All participants will receive a standardized 6-week physiotherapy program consisting of three supervised sessions per week.
Outcome assessments will be performed at three time points: baseline (pre-intervention), mid-intervention (3 weeks), and post-intervention (6 weeks). The primary and secondary outcome measures include pain intensity measured using the Visual Analog Scale (VAS), physical function using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), proprioception using the Joint Position Sense (JPS) test, gait performance using the Six-Minute Walk Test (6MWT), health-related quality of life using the Short Form-36 (SF-36), and treatment compliance. The study will examine changes in these outcomes over time and compare the effectiveness of the intervention between male and female participants.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
A structured six-week Sensory-Modulated Graded Weight-Bearing Physiotherapy Programme consisting of three supervised sessions per week (18 sessions total). Each session includes warm-up, sensory modulation, proprioceptive training, graded weight-bearing strengthening, functional mobility exercises, and cool-down activities. The programme progresses through three phases: Weeks 1-2 focus on sensory activation and proprioceptive training; Weeks 3-4 on graded weight-bearing strengthening; and Weeks 5-6 on functional weight-bearing integration. Exercises are progressed according to participant tolerance, pain severity, and functional performance. Both male and female groups receive the same intervention.
Time frame: Baseline, Week 3, and Week 6
To evaluate the change in pain intensity following a 6-week Sensory-Modulated Graded Weight Bearing Physiotherapy program in patients with knee osteoarthritis.
Time frame: Baseline, Week 3, and Week 6
To assess changes in physical function following Sensory-Modulated Graded Weight-Bearing Physiotherapy.
Time frame: Baseline, Week 3, and Week 6
To assess changes in knee joint proprioception following Sensory Modulated Graded Weight-Bearing Physiotherapy
Time frame: Baseline, Week 3, and Week 6
To assess changes in gait performance following Sensory Modulated Graded Weight-Bearing Physiotherapy
Time frame: Baseline, Week 3, and Week 6
To assess changes in health-related quality of life following Sensory-Modulated Graded Weight-Bearing Physiotherapy
Time frame: At the end of the 6 week intervention
To assess participants adherence to the prescribed 6-week Sensory Modulated Graded Weight Bearing Physiotherapy program. Treatment compliance determine based on the percentage of complete supervised treatment session
Shifa Tameer-e-Millat University
Other
Acronym: GSMGWBP
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07367126
Arthritis, Joint Diseases
Istanbul, Turkey (Türkiye)
View Trial DetailsNCT07262931
Arthritis, Joint Diseases
Lahore, Punjab Province, Pakistan
View Trial DetailsNCT07777757
Arthritis, Joint Diseases
Hong Kong, Sandy Bay
View Trial DetailsNCT07767409
Arthritis, Joint Diseases
Singapore
View Trial Details