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OpenTrials
Not yet recruiting

NCT Number: NCT07782619

Agreement of Two OCT Biometers: A Pilot Study

The purpose of this study is to compare the measurements obtained with two different biometers, UNITY Dx and Anterion. In eye care, a biometer is a device that uses laser technology to take highly precise measurements of the eye's internal structures. It is most frequently used to help determine the exact power of the intraocular lens (IOL) needed before cataract removal.

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

The Eye Institute of Utah

Salt Lake City, Utah, 84107, United States

About this study

The study population will consist of male and female adult subjects with a normal cornea (up to 10 subjects), keratoconus (up to 10 subjects), prior corneal laser vision correction (up to 10 subjects), current and habitual contact lens wear (up to 10 subjects), or dry eye (up to 10 subjects). In this single visit study, subjects will have data collected on one eye (unilateral) only. If both eyes meet the entry criteria, the right eye will be designated as the study eye.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Have healthy, clear corneas for the normal cohort;
  • Have documented keratoconus for the keratoconus cohort;
  • Have reported use of daily contact lens use for the contact lens cohort;
  • Have documented dry eye, consisting of signs and symptoms for the dry eye cohort;
  • Has had previous keratorefractive surgery for the post-refractive surgery cohort;
  • Able to comprehend and sign the informed consent form.

Exclusion criteria

  • Active ocular infection or inflammation;
  • Unable to fixate due to nystagmus or other eye movement abnormality (e.g., significant strabismus);
  • Any ocular disease and/or condition that, in the investigator's clinical judgment, may put the subject at significant risk, may compromise study result or may interfere significantly with the subject's participation in the study.

Treatment and study plan

UNITY DX

Device

Investigational non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and their optical properties

ANTERION

Device

Commercially available non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and their optical properties

Primary outcomes

  1. Regression-Based Axial Length (R-AL)

    Time frame: Day 1

    Regression-based Axial Length (R-AL) is the distance from the anterior surface of the cornea to the retina at the back of the eye, measured along the visual axis. R-AL will be measured by the device and reported in microns.

Study contacts

Contact information is provided by the study sponsor or research team.

Alcon Call Center

CONTACT

[email protected]

1-888-451-3937

Sponsors and collaborators

Lead sponsor

Alcon Research

Industry

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Aug 24, 2026
Registry last updated
Aug 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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