Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07780812

Evaluation of Speech and Voice Biomarkers in Association With Burnout

This project aims to explore how speech patterns and voice characteristics can be used to detect signs of burnout and stress in physicians.

Recruiting

Interested in participating?

Request Info

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Minneapolis Heart Institute

Minneapolis, Minnesota, 55407, United States

Location status: Recruiting

Location contact

Michaella Alexandrou, MD

CONTACT

[email protected]

612-863-4768

About this study

Aim 1: To determine the association amongst acoustic features, derived from speech and voice samples, and burnout and mental stress measured using questionnaires in healthcare workers (physicians, nurses, advanced practice providers, and other clinical staff) at the Minneapolis Heart Institute.

Aim 2: To compare the effects of the CalmiGo stress management device on acoustic features, derived from voice samples, and burnout and mental stress assessed using questionnaires in healthcare workers (physicians, nurses, advanced practice providers, and other clinical staff) with burnout (Mini-Z 2.0 single item burnout score 3, 4 or 5 on 5 choice item, question 2) against no specific guidance.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Aim 1 Inclusion Criteria:

  • Adult individuals (18 years-old or older)
  • Healthcare workers (physicians, nurses, advanced practice providers, and other clinical staff) at the Minneapolis Heart Institute
  • Ability to use the CalmiGo device for 12-weeks
  • Willingness to complete study questionnaires, have speech and voice samples recorded and analyzed at the beginning of the study.

AIM 2 Inclusion criteria

  • Adult individuals (18 years-old or older)
  • Healthcare workers (physicians, nurses, advanced practice providers, and other clinical staff) with burnout (Mini-Z 2.0 single item burnout score 3, 4 or 5 on 5 choice item, question 2).
  • Ability to use the CalmiGo device for 12-weeks
  • Willingness to complete study questionnaires, have speech and voice samples recorded and analyzed at the beginning and end of the study.

AIM 1 and 2Exclusion Criteria:

  • English is not their preferred language
  • Current or known history of a voice or speech disorder
  • Current or history of laryngeal malignancy
  • History of laryngeal surgery
  • Known diagnosis of a voice disorder: Vocal Cord Nodules, Polyp, or Cyst; Vocal Cord Paralysis; Dysphonia
  • Laryngitis
  • Dyslexia
  • Muscle Tension
  • Aphasia
  • Stuttering
  • Dysarthria
  • Essential Tremor
  • Neurodegenerative conditions (Parkinson's Disease, Multiple Sclerosis, ALS, MSA, Dementia)
  • Severe psychiatric disorder (depression, anxiety, bipolar, schizophrenia, etc.)

Treatment and study plan

CalmiGo

Device

use of the calmigo device 3 times a day for 3 minutes at a time across 12 weeks

Primary outcomes

  1. Mini-Z 2.0 survey score

    Time frame: 12 weeks

    Burnout as measured by response to the Mini-Z 2.0 survey. A lower score indicates higher burnout

  2. Maslach Burnout Inventory (MBI) survey score

    Time frame: 12 weeks

    Burnout as measured by response to the Maslach Burnout Inventory (MBI) survey. Higher score indicated increased burnout

Study contacts

Contact information is provided by the study sponsor or research team.

Bavana Rangan, BDS, MPH

CONTACT

Michaella Alexandrou, MD

CONTACT

[email protected]

612-863-4768

Sponsors and collaborators

Lead sponsor

Minneapolis Heart Institute Foundation

Other

Collaborators

  • Allina Health

Registry information

Acronym: Voice-B

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Aug 24, 2026
Registry last updated
Aug 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.