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NCT Number: NCT07777172

Recto-Intercostal Fascial Plane and External Oblique Intercostal Blocks for Pain in Laparoscopic Cholecystectomyin Laparoscopic Cholecystectomy

Laparoscopic cholecystectomy is a common surgical procedure that can cause significant postoperative pain, particularly originating from trocar insertion sites. Regional anesthesia techniques are frequently used as part of multimodal analgesia to improve patient comfort.

This randomized controlled trial aims to evaluate the efficacy of adding a recto-intercostal fascial plane block (RIFPB) to an external oblique intercostal plane block (EOIPB). Patients scheduled for elective laparoscopic cholecystectomy will be randomly assigned to receive either an EOIPB alone or a combination of EOIPB and RIFPB. The primary objective is to determine if the combined block approach provides superior postoperative analgesia, evaluated by compared to the EOIPB alone.

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Key information

Conditions

Postoperative Pain Cholecystectomy, Laparoscopic Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ankara Etlik City Hospital

Ankara, Yenimahalle\Ankara, 06170, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged between 18 and 75 years
  • American Society of Anesthesiologists (ASA) physical status I, II, or III
  • Patients scheduled for elective laparoscopic cholecystectomy

Exclusion criteria

  • Known allergy to local anesthetics
  • Infection at the procedure/injection site
  • Severe coagulopathy or use of anticoagulants
  • Chronic opioid consumption or history of neuropathic pain

Treatment and study plan

Group EOIPB (External Oblique Intercostal Plane Block)

Procedure

Patients will undergo bilateral EOIPB procedure using 20 ml of 0.20% bupivacaine on each side under ultrasound guidance.

Group EOIPB + RIFPB (Combined Blocks)

Procedure

Patients will undergo bilateral EOIPB and RIFPB procedures under ultrasound guidance using 20 ml of 0.20% bupivacaine for the EOIPB block and 15 ml of 0.20% bupivacaine for the RIFPB on each side.

Primary outcomes

  1. Postoperative Pain Intensity

    Time frame: 4 hours after surgery

    Pain will be assessed using a visual analog scale from 0 mm (no pain) to 100 mm (worst pain) at rest. Pain assessment at rest will be made at 4 hours after surgery.

Secondary outcomes

  1. Postoperative Pain Intensity

    Time frame: Up to 24 hours

    Pain will be assessed using a visual analog scale from 0 mm (no pain) to 100 mm (worst pain) at rest. Pain assessment at rest will be made at 1, 8, 12, and 24 hours after surgery.

  2. Postoperative Pain Intensity

    Time frame: Up to 24 hours

    ain will be assessed using a visual analog scale from 0 mm (no pain) to 100 mm (worst pain) while coughing. Pain assessment will be made at 1, 4, 8, 12, and 24 hours after surgery.

  3. Total Postoperative Opioid Consumption

    Time frame: Up to 24 hours

    The total amount of opioid consumed by the patient will be recorded.

  4. Severity of Postoperative Nausea and Vomiting (PONV)

    Time frame: Up to 24 hours

    The severity of postoperative nausea will be assessed using an 11-point numerical rating scale (NRS), ranging from 0 to 10, where 0 indicates no nausea and 10 indicates the worst possible nausea. Vomiting will be recorded as the number of vomiting episodes. Nausea severity will be assessed at 1, 4, 8, 12, and 24 hours after surgery. Higher NRS scores indicate greater nausea severity.

Study contacts

Contact information is provided by the study sponsor or research team.

Musa Ass. Prof Zengin

CONTACT

[email protected]

05071302750

İbrahim MD Topcu

CONTACT

[email protected]

05437860316

Sponsors and collaborators

Lead sponsor

Ankara Etlik City Hospital

Other Gov

Registry information

Official study title

Does the Addition of Recto-Intercostal Fascial Plane Block to External Oblique Intercostal Plane Block Improve the Quality of Postoperative Analgesia in Laparoscopic Cholecystectomy? A Randomized Controlled Trial

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Aug 20, 2026
Registry last updated
Aug 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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