Skip to main content
OpenTrials
Active, not recruiting

NCT Number: NCT07776834

Generative AI-Supported Personalized Education Compared With Printed Material for Adults With Hypertension

This study evaluates whether generative artificial intelligence-supported personalized education can improve hypertension knowledge and medication adherence in adults with hypertension compared with standard printed educational material. A total of 88 adults with hypertension are included in the study. Participants are assigned to either an intervention group or a control group. The control group receives a printed hypertension education booklet. The intervention group receives personalized educational content prepared using generative artificial intelligence based on individual characteristics and needs, together with weekly WhatsApp or SMS messages, voice messages, and brief telephone follow-up. The intervention lasts four weeks, and final assessments are performed in the fifth week. Hypertension knowledge, medication adherence self-efficacy, and blood pressure are assessed before and after the intervention. It is expected that personalized education will improve hypertension knowledge and medication adherence compared with printed education.

Active, not recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Conditions

Hypertansion Behavior Health Behavior Medication Adherence Patient Acceptance of Health Care Patient Compliance Treatment Adherence and Compliance

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Akdeniz University Hospital

Antalya, 07070, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Voluntary agreement to participate in the study
  • Diagnosis of hypertension
  • Use of antihypertensive medication for at least 6 months
  • Medication adherence self-efficacy score of 26 or lower
  • Age 18 years or older
  • Ability to read and write in Turkish
  • General health status adequate for communication
  • Ability to read SMS messages and use WhatsApp

Exclusion criteria

  • Withdrawal from the study after enrollment
  • Inability to be reached by telephone during the follow-up period

Treatment and study plan

Standard Hypertension Education

Behavioral

Participants receive standard hypertension education including medication-related information and a printed hypertension education booklet developed based on expert recommendations.

Generative AI-Supported Personalized Hypertension Education

Behavioral

Participants receive personalized hypertension education generated using generative artificial intelligence based on individual characteristics, needs, baseline information, and standardized hypertension education content. The intervention is delivered over four weeks through weekly WhatsApp or SMS messages and voice messages. Brief structured telephone follow-up is provided in the first and fourth weeks.

Primary outcomes

  1. Mean Change From Baseline in Medication Adherence Self-Efficacy Scale-Short Form (MASES-SF) Total Score at Week 5

    Time frame: Baseline and Week 5

    Medication adherence self-efficacy will be assessed using the 13-item Medication Adherence Self-Efficacy Scale-Short Form (MASES-SF). Each item is scored from 1 (not at all sure) to 4 (very sure), resulting in a total score ranging from 13 to 52. Higher scores indicate greater self-efficacy for adhering to antihypertensive medication. The change in total score from baseline to Week 5 will be evaluated.

  2. Mean Change From Baseline in Hypertension Knowledge-Level Scale (HK-LS) Total Score at Week 5

    Time frame: Baseline and Week 5

    Hypertension knowledge will be assessed using the 22-item Hypertension Knowledge-Level Scale (HK-LS). The scale includes six domains: definition, medical treatment, medication adherence, lifestyle, diet, and complications. Responses are recorded as true, false, or do not know, and each correct response receives 1 point. Higher scores indicate greater hypertension knowledge, and a score of 16 or above indicates a high level of hypertension knowledge. The change in total score from baseline to Week 5 will be evaluated.

Secondary outcomes

  1. Mean Change From Baseline in Systolic Blood Pressure at Week 5

    Time frame: Baseline and Week 5

    Systolic blood pressure will be measured in mmHg at baseline and Week 5. The change in systolic blood pressure from baseline to Week 5 will be evaluated.

  2. Mean Change From Baseline in Diastolic Blood Pressure at Week 5

    Time frame: Baseline and Week 5

    Diastolic blood pressure will be measured in mmHg at baseline and Week 5. The change in diastolic blood pressure from baseline to Week 5 will be evaluated.

Sponsors and collaborators

Lead sponsor

Akdeniz University

Other

Registry information

Official study title

The Effect of Generative Artificial Intelligence-Supported Personalized Education Compared With Printed Material on Hypertension Knowledge and Medication Adherence in Adults With Hypertension

Acronym: GenAI-HYPER

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 20, 2026
Registry last updated
Aug 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.