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NCT Number: NCT07775690

Open Reduction and Internal Fixation of Humeral Midshaft Fracture: Anterior Versus Posterior Plate Fixation

About 13 out of 10,000 patients get a humeral shaft fracture each year, accounting for 1.0-3.0% of all fractures. The central part of the humerus is where 60% of all humeral fractures occur. A midshaft humerus fracture typically happens because of a direct impact to the upper arm. Trauma, such as falls, motor vehicle accidents, or motorcycle accidents, is the most common cause of fractures. Internally fixing humeral shaft fractures is often accomplished by a variety of surgical techniques. Usually, the posterior technique is used to repair distal and mid-shaft fractures. However, the posterior technique necessitates lateral or prone stance. The aim of this study comparing the outcomes of internal fixation and open reduction of humeral midshaft fractures utilizing anterior and posterior plate fixation. We want to conduct this study to get evidence to confirm whether which approach is more appropriate and more successful in such fractures. Moreover, the findings of this research could profoundly influence clinical outcomes by guiding orthopedic surgeons in their decision-making for management of humeral midshaft fracture.

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Key information

Conditions

Humeral Shaft Fractures

Age range

16 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sahiwal Teaching Hospital

Sāhīwāl, Punjab Province, 57450, Pakistan

Location status: Recruiting

Location contact

Dr Kashif Raza Khan, MBBS, FCPS

CONTACT

[email protected]

+923338960200

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Presenting with humeral midshaft fracture (presence of fracture in the middle part or center of humerus )

Exclusion criteria

  • Patients with pathological or open fractures, concomitant fractures or ligament or tendon ruptures of elbow or shoulder joints (on clinical examination)
  • Patients presented after 14 days of injury, partial or complete disability of the elbow or shoulder joint on the affected side before injury
  • Previous surgical procedure on same side
  • Presence of neurovascular complications
  • Apparent dementia or other psychological problems

Treatment and study plan

Open Reduction Internal Fixation (ORIF) using Anterior approach for plate fixation

Procedure

In group A, participants will undergo ORIF by using anterior approach for plate fixation. Operative time will be noted. After surgery, patients will be shifted to post-surgical orthopedic wards and will be discharged from there. All patients will be followed-up in OPD for 3 months.

Open Reduction Internal Fixation (ORIF) using Posterior approach for plate fixation

Procedure

In group B, participants will undergo ORIF by using posterior approach for plate fixation. Operative time will be noted. After surgery, patients will be shifted to post-surgical orthopedic wards and will be discharged from there. All patients will be followed-up in OPD for 3 months.

Primary outcomes

  1. Operative time

    Time frame: 3 Months

    It will be assessed by using in terms of minutes required to perform surgery from time of incision given in the skin until closure of skin with stitches.

  2. Bone union

    Time frame: 3 Months

    It will be labeled if there is detectable callus bridge or at least three visible cortices on radiographs

  3. American Shoulder and Elbow Surgeons Score (ASES)

    Time frame: 3 Months

    It will be assessed after 3 months of surgery

Study contacts

Contact information is provided by the study sponsor or research team.

Dr Jahanzaib Ramay, MBBS

CONTACT

[email protected]

+923317787687

Sponsors and collaborators

Lead sponsor

Dr Jahanzaib Ramay

Other

Collaborators

  • Sahiwal Teaching Hospital

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 20, 2026
Registry last updated
Aug 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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