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NCT Number: NCT07775066

Pattern of AFP in Chhidren Admitted at Sohag University Hospital

This study is observational study aims to study the Clinical profile, Possible risk factors and Outcome of Acute flaccid paralysis in children at Sohag University Hospital.

Our study will include all children admitted to pediatric emergency and intensive care units with claim or suspicion to have acute falccid paralysis

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Key information

Conditions

Acute Flaccid Paralysis AFP Autoimmune Diseases Autoimmune Diseases of the Nervous System Central Nervous System Diseases Central Nervous System Infections Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Gullian Barre Syndrome Immune System Diseases Infections Myelitis Myelitis, Transverse Neoplasms Neoplasms by Site Nervous System Diseases Nervous System Neoplasms Neurodegenerative Diseases Neuroinflammatory Diseases Paraneoplastic Syndromes Paraneoplastic Syndromes, Nervous System Spinal Cord Diseases Transverse Myelitis acute flaccid myelitis

Age range

1 month–16 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag University Hospital

Sohag, Sohag Governorate, 82511, Egypt

About this study

This study is a single center, Observational Cross Sectional Hospital Based study aims to study the Clinical profile, Possible risk factors and Outcome of Acute flaccid paralysis in children aged from birth to 18 years old at Sohag University Hospital.

All included children with acute flaccid paralysis will be subjected to:

All routine investigation (complete blood count, C.R.P, blood gases, serum electrolytes, coagulation profile, liver and kidney function test) Imaging when indicated (Brain C.T, Brain and spine MRI, Nerve Conduction Study)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients admitted to pediatric emergency and intensive care units with claim or suspected to have acute flaccid paralysis aged from 1 month Up to 16 years old

Exclusion criteria

  • Children with flaccid paralysis due to causes other than neurogenic causes. No clear history or clinical picture of definite neurological cause. incomplete clinical data.

Treatment and study plan

Observitional follow-up

Other

No expiremental intervention. Data will be collected from routine cinical care, medical records and folow up visits according to standard hospital protocols

Primary outcomes

  1. Full recovery

    Time frame: 1 Year

    Full restoration of muscle strength and function.

Secondary outcomes

  1. Partial Recovery with Residual Weakness

    Time frame: 1 Year

    Persistent muscle weakness despite improvement

  2. Permanent Paralysis

    Time frame: 1 Year

    Irreversible loss of motor function due to destruction of motor neurons or severe nerve injury

Study contacts

Contact information is provided by the study sponsor or research team.

Mohamed Aboelhamd Ali

CONTACT

[email protected]

01069741666

Sponsors and collaborators

Lead sponsor

Mohamed Aboelhamd Ali

Other

Registry information

Official study title

Spectrum of Acute Flaccid Paralysis in Children Admitted at Sohag University Hospital

Acronym: AFP-SUH

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Aug 20, 2026
Registry last updated
Aug 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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