Efficacy of Tramadol With Ropivacaine for Modified Pectoral Nerve Block in Breast Cancer Surgery

In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy. The patients will be divided into two groups one group will receive modified pectoral nerve block with local anesthetic ropivacaine combined with tramadol and other group will receive pectoral nerve block with ropivacaine only

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Key information

Conditions

Postoperative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dr Faisal Masood teaching Hospital Sargodha

Sargodha, Punjab Province, 40100, Pakistan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Female Patients aged 20-70 years
Patients scheduled for elective unilateral modified radical mastectomy
Patients with ASAI andII physical status.

Exclusion criteria

Patients on anticoagulant therapy.
Patients with a BMI≥35 kg/m3.
Patients with a history of allergy to local anesthetics.
Patients with significant neurological or psychiatric disorders.
Pregnant patients.

Treatment and study plan

pectoral nerve block

Procedure

One group will receive ropivacaine with tramadol in modified pectoral nerve block

Primary outcomes

Postoperative Pain with visual analogue scale

Time frame: 24 hours postoperatively

Post operatively pain will be accessed by visual analogue scale . Visual analogue scale (VAS) scale has score from 0 to 10 where 0 score indicate no or minimal pain and score of 10 indicate worst possible pain.

Sponsors and collaborators

Lead sponsor

Sargodha Medical College

Other

Registry information

Official study title

Comparison of Post Operative Analgesia Between 0.25% Ropivacaine and 0.25% Ropivacaine Combined With Tramadol in Ultrasound Guided Modified Pectoral Nerve Block for Patient Undergoing Modified Radical Mastectomy.

Important dates

Study start: 2026
Primary completion: 2027
Study completion: 2027
First posted: Aug 20, 2026
Registry last updated: Aug 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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