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NCT Number: NCT07773194

Progressive Muscle Relaxation and Deep Breathing Exercises in Patients With COPD

This randomized controlled trial evaluated the effects of progressive muscle relaxation and deep breathing exercises on fatigue and sleep quality in patients with chronic obstructive pulmonary disease (COPD). A total of 90 patients were assigned to three groups: a progressive muscle relaxation exercise group, a deep breathing exercise group, and a control group. Participants in the intervention groups were taught their assigned exercises individually and were instructed to practice them daily at home for 8 weeks. The control group received no study intervention during this period. Fatigue and sleep quality were assessed before the intervention and at the end of the 8-week study period.

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Key information

About this study

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition that can negatively affect patients' physical and psychological well-being. Fatigue and impaired sleep quality are common symptoms that may adversely affect daily functioning and quality of life. Non-pharmacological interventions that can be easily practiced by patients may contribute to symptom management.

The aim of this randomized controlled trial was to evaluate the effects of progressive muscle relaxation and deep breathing exercises on fatigue and sleep quality in patients with COPD.

The study included 90 patients with COPD who were randomly assigned to three parallel groups, with 30 participants in each group: a progressive muscle relaxation exercise group, a deep breathing exercise group, and a control group. Randomization was performed using random numbers generated through the Random Integer Generator on Random.org, and group assignment was conducted by an independent researcher. Due to the nature of the interventions, blinding was not applied.

Participants assigned to the progressive muscle relaxation group received individual training on progressive muscle relaxation exercises. The initial training lasted approximately 30-40 minutes. Participants were provided with relaxation exercise audio recordings for home practice and were instructed to perform the exercises every morning for 8 weeks. Weekly telephone contact was maintained during the intervention period.

Participants assigned to the deep breathing exercise group received individual practical training in pursed-lip breathing exercises. The training lasted approximately 20-25 minutes, and participants practiced the technique under guidance to ensure that they could perform it correctly. They were instructed to perform the breathing exercises every morning at home for 8 weeks.

Participants assigned to the control group received no study intervention during the 8-week study period.

Fatigue and sleep quality were evaluated at baseline and at the end of 8 weeks using the Chronic Obstructive Pulmonary Disease and Asthma Fatigue Scale and the Pittsburgh Sleep Quality Index, respectively.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed with chronic obstructive pulmonary disease (COPD) according to GOLD criteria at least 6 months before enrollment.

Able to communicate verbally. No severe hearing or visual impairment. No serious medical condition or serious complication related to COPD.

Exclusion criteria

  • Presence of a perceptual disorder or psychiatric condition that impairs communication.

Presence of a serious complication related to COPD.

Treatment and study plan

Progressive Muscle Relaxation

Behavioral

Participants received individual training on progressive muscle relaxation exercises. The training lasted approximately 30-40 minutes. Relaxation exercise audio recordings were provided to support home practice. Participants were instructed to perform the progressive muscle relaxation exercises every morning at home for 8 weeks. Weekly telephone contact was maintained during the intervention period.

Deep Breathing Exercise

Behavioral

Participants received individual practical training in pursed-lip breathing exercises. The technique was explained verbally and practiced under guidance in a quiet environment to ensure correct performance. The training lasted approximately 20-25 minutes. Participants were instructed to perform the breathing exercises every morning at home for 8 weeks.

Primary outcomes

  1. Fatigue Level

    Time frame: Baseline and 8 weeks after the start of the intervention

    Fatigue was assessed using the Chronic Obstructive Pulmonary Disease and Asthma Fatigue Scale. The scale consists of 12 items. Item scores are summed and transformed to a total score ranging from 0 to 100. Higher scores indicate greater levels of fatigue.

  2. Sleep Quality

    Time frame: Baseline and 8 weeks after the start of the intervention

    Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). The global PSQI score ranges from 0 to 21, with higher scores indicating poorer sleep quality. A total score of 5 or higher indicates poor sleep quality.

Sponsors and collaborators

Lead sponsor

Firat University

Other

Registry information

Official study title

The Effect of Progressive Muscle Relaxation and Deep Breathing Exercises on Fatigue and Sleep Quality in Patients With COPD: A Randomized Controlled Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 19, 2026
Registry last updated
Aug 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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