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NCT Number: NCT07769281

Safety and Efficacy of NeuroTechR3 System for Upper Extremity Recovery After Stroke

This research aims to understand the feasibility and effectiveness of using the NeuroTechR3 System to improve upper extremity function after stroke.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Brooks Rehabilitation Hospital - Bartram Campus

Jacksonville, Florida, 32258, United States

Location status: Recruiting

Location contact

Hannah Grimes

CONTACT

[email protected]

904-528-3159

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years at the time of enrollment
  • Diagnosed with stroke
  • No other peripheral or central neurological condition limiting target upper extremity function (previous stroke is ok)
  • Indicated for upper extremity training procedures by participant's treating physician, occupational therapist, or physical therapist
  • Capable of providing informed consent
  • Participant demonstrates active extension of wrist and activation of at least two other digits plus thumb activation

Exclusion criteria

  • In the opinion of the investigators, the study is not safe or appropriate for the participant, and/or the participant is unlikely to return for the follow-up visits per the protocol to return the device at 4 weeks post discharge
  • Visual impairment that would severely limit ability to see a computer screen for participation in sessions, including severe spatial neglect making the person unable to interact with an entire computer screen
  • Inability to follow a 3-step motor command
  • Severe upper extremity tone that will limit participation in study
  • No internet access at home
  • Severe receptive aphasia
  • Severe arthritis that limits hand and arm movements
  • Not independent in functional activities/mobility prior to stroke

Treatment and study plan

NeuroTechR3 Computer Rehabilitation System

Device

Participants will complete three sessions a week, each lasting for 30 minutes. The sessions consist of upper extremity rehabilitation games on the computer.

Primary outcomes

  1. Upper Extremity Strength and Function

    Time frame: Pre-intervention, mid-intervention within 3 days of discharging from the inpatient rehabilitation facility, and post-intervention at 6 weeks.

    The Fugle-Meyer test is a simple, standardized test used to assess a person's exercise capacity and functional mobility. An increase in score reflects an improvement in mobility and upper extremity function.

  2. Questionnaires

    Time frame: Mid-intervention within 3 days of discharging from the inpatient rehabilitation facility and post-intervention at 6 weeks.

    The System Usability Scale measures the perceived usability, ease of use, and learnability of the system. An increase in score indicates better usability.

Secondary outcomes

  1. Care Transition

    Time frame: Pre-intervention, mid-intervention within 3 days of discharging from the inpatient rehabilitation facility, and post-intervention at 6 weeks.

    The NeuroTechR3 System evaluates range of motion, speed, and accuracy for the hand and arm. An increase in kinematic data indicates improved functioning.

Study contacts

Contact information is provided by the study sponsor or research team.

Hannah Grimes

CONTACT

[email protected]

904-528-3159

Sponsors and collaborators

Lead sponsor

Brooks Rehabilitation

Other

Collaborators

  • NeuroTechR3

Registry information

Acronym: R3

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 17, 2026
Registry last updated
Aug 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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