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OpenTrials
Completed

NCT Number: NCT07769112

Comparative Efficacy of Oil Pulling and Chlorhexidine on Plaque Induced Gingivitis

This randomized clinical trial aims to compare the efficacy of chlorhexidine and coconut oil in plaque-induced gingivitis patients. The study seeks to determine whether coconut oil pulling can provide comparable anti-plaque and anti-inflammatory effects to chlorhexidine mouthwash while producing fewer side effects. A total of 80 participants who diagnosed as plaque induced gingivitis will be randomly allocated into two equal groups (coconut and chlorhexidine). Clinical parameters, including Plaque Index and Gingival Index, will be assessed at baseline, day 7, day 14, and day 21 to evaluate changes in plaque and gingival inflammation following the interventions.

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Key information

Conditions

Plaque Induced Gingivitis Dental Deposits Dental Plaque Gingival Diseases Gingivitis Infections Mouth Diseases Periodontal Diseases Stomatognathic Diseases Tooth Diseases

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dr. Nida Tariq

Karachi, Sindh, 75330, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individual aged between 22-60years.
  • Individual who have retained 28 no of teeth in the mouth.
  • Individuals who have diagnosed as plaque induced gingivitis along with mild to moderate gingival inflammation.

Exclusion criteria

  • Individual who have any systemic medical illness
  • Multiple extractions, overhang restoration, wearing any appliance
  • Periodontal problem with pocket depth more than 3mm
  • Current or recent history of antibiotic consumption
  • Non compliance that is unable to maintain their hygiene -

Treatment and study plan

Chlorhexidine mouthwash (0.12%)

Other

Participants will use 0.12% chlorhexidine mouthwash twice daily for 21 days.

coconut oil pulling

Other

Participants will rinse with coconut oil once daily for 10-15 minutes for 21 days.

Primary outcomes

  1. Reduction in Gingival Inflammation

    Time frame: Baseline, Day 7, Day 14, and Day 21

    To assess the gingival inflammation using Gingival Index scores in participants receiving chlorhexidine mouthwash and coconut oil pulling therapy

Secondary outcomes

  1. Reduction in Dental Plaque

    Time frame: Baseline, Day 7, Day 14, and Day 21

    Evaluation of dental plaque accumulation using Plaque Index scores among study participants.

Sponsors and collaborators

Lead sponsor

Liaquat College of Medicine and Dentistry

Other

Registry information

Official study title

Comparative Efficacy of Oil Pulling and Chlorhexidine on Plaque Induced Gingivitis: Randomized Clinical Trial

Acronym: chx oilpulling

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 17, 2026
Registry last updated
Aug 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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