Evaluation of Dermal Acceptability and Comedogenic and Acnegenic Potential of a Cosmetic Product

Inclusion criteria

• Female participants aged 18 to 45 years.
• Participants with oily and acne-prone skin.
• Intact skin in the area intended for application and assessment of the investigational product.
• Willingness to comply with all study procedures and attend scheduled visits and assessments.
• Ability to understand the study requirements, provide written informed consent, and sign the Informed Consent Form (ICF).

Exclusion criteria

• Pregnant or breastfeeding women, or women at risk of becoming pregnant during the study.
• Use of anti-inflammatory, immunosuppressive, or antihistamine medications within 3 weeks prior to screening.
• Skin conditions or marks in the study area that may interfere with the evaluation of skin reactions, including vascular malformations, scars, excessive hair growth, multiple nevi, or sunburn.
• History of atopic conditions or allergy to cosmetic products.
• Active skin diseases and/or lesions in the assessment area or elsewhere on the body.
• Immunosuppression due to medication use or active disease.
• Uncontrolled endocrine disorders.
• Relevant medical history or current evidence of alcohol or substance abuse.
• Known history or suspected intolerance to products of the same category as the investigational product.
• Intense sun exposure within 15 days prior to assessment.
• Aesthetic or dermatological treatments within 4 weeks prior to assessment.
• Any other condition that, in the investigator's opinion, may interfere with study participation, study evaluations, or justify exclusion from the study.